| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2167514 | B | Inhibition of human BBOX1 by fluorescence based assay | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 2. | ALA3242134 | B | Inhibition of BBOX (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 3. | ALA3242135 | B | Inhibition of human recombinant BBOX expressed in Saccharomyces cerevisiae AH22 assessed as formation of carnitine from gamma-butyrobetaine preincubated for 15 mins measured after 30 mins by UPLC-MS/MS analysis | Homo sapiens | 52 | assay format | Scientific Literature | ||
| 4. | ALA3242136 | B | Ratio of mildronate IC50 to compound IC50 for human recombinant BBOX | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 5. | ALA3242137 | B | Binding affinity to purified human BBOX by isothermal titration calorimetry analysis | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 6. | ALA3382782 | B | Inhibition of human BBOX pre-incubated for 1 min using TBS-protected fluorescein probe and Fe (II) (Fe(NH4)2(SO4)2 salt by fluoride release assay | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 7. | ALA3382783 | B | Inhibition of human BBOX pre-incubated for 10 mins using TBS-protected fluorescein probe and Fe (II) (Fe(NH4)2(SO4)2 salt by fluoride release assay | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 8. | ALA3382784 | B | Inhibition of human BBOX pre-incubated for 15 mins using TBS-protected fluorescein probe and Fe (II) (Fe(NH4)2(SO4)2 salt by fluoride release assay | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 9. | ALA3382785 | B | Inhibition of human BBOX pre-incubated for 20 mins using TBS-protected fluorescein probe and Fe (II) (Fe(NH4)2(SO4)2 salt by fluoride release assay | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 10. | ALA3382786 | B | Inhibition of human BBOX pre-incubated for 25 mins using TBS-protected fluorescein probe and Fe (II) (Fe(NH4)2(SO4)2 salt by fluoride release assay | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 11. | ALA3382787 | B | Induction of Zn(II) from human BBOX assessed as zinc release by fluorescence based assay | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 12. | ALA3382788 | B | Binding affinity to human BBOX assessed as quenching of intrinsic tryptophan fluorescence at 50 to 200 uM in presence of Fe(II) | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 13. | ALA3382789 | B | Binding affinity to human BBOX assessed as quenching of intrinsic tryptophan fluorescence at 50 to 200 uM in absence of Fe(II) | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 14. | ALA3382790 | B | Binding affinity to human BBOX assessed as covalent modification by measuring PhSe group mass shift at 1 equivalent dose by LC-MS method | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 15. | ALA3382791 | B | Binding affinity to human BBOX assessed as covalent modification by measuring PhSe group mass shift at 1 equivalent dose after 24 hrs by LC-MS method | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 16. | ALA3383442 | B | Binding affinity to human BBOX assessed as covalent modification by measuring PhSe group mass shift at 10 equivalent dose after 24 hrs by non-denaturating LC-MS method | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 17. | ALA3383443 | B | Binding affinity to human BBOX by tryptophan fluorescence quenching binding assay | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 18. | ALA3383444 | B | Binding affinity to human BBOX in presence of Fe(II) by tryptophan fluorescence quenching binding assay | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 19. | ALA3821757 | B | Inhibition of human BBOX using GBBF as substrate in presence of 2OG and Fe2+ using TBS-protected fluorescein probe by fluoride release assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 20. | ALA5229137 | B | Inhibition of BBOX1 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature |
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