| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2173264 | B | Competitive binding affinity to full length human SMYD2 amino acid 1 to 433 expressed in Escherichia coli BL21 (DE3) after 90 mins by radioactive filter-binding assay in presence of P53 peptide | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 2. | ALA2173342 | B | Inhibition of full length human SMYD2 amino acid 1 to 433 expressed in Escherichia coli BL21 (DE3) using Biotinaminohexanoyl- GSRAHSSHLKSKKGQSTSRH as substrate after 75 mins by AlphaScreen assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 3. | ALA2330195 | B | Inhibition of SMYD2 (unknown origin) using P53 (361 to 380) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenosylmethionine | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 4. | ALA3111729 | B | Inhibition of SMYD2 (unknown origin)-mediated incorporation of methyl group from [3H]-SAM into peptide substrate up to 50 uM by scintillation proximity assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 5. | ALA3378779 | B | Inhibition of SMYD2 (unknown origin) assessed as incorporation of tritium-labeled methyl group to lysine or arginine residues of peptide substrate by radioactive assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 6. | ALA3399140 | B | Inhibition of SMYD2 (unknown origin) by HMT assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 7. | ALA3399147 | B | Inhibition of SMYD2 (unknown origin) at 10 uM by HMT assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA3420707 | B | Inhibition of recombinant human full-length SMYD2 (1 to 433) using biotin-aminohexanoyl GSRAHSSHLKSKKGQSTSRH as substrate after 75 mins by AlphaScreen assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA3420708 | B | Binding affinity to recombinant human full-length SMYD2 (1 to 433) by ITC analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA3420944 | B | Inhibition of SMYD2 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA3420958 | B | Inhibition of SMYD2 in human KYSE-150 cells assessed as reduction of monomethylation of p53 K370 by sandwich ELISA method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA3592282 | B | Inhibition of SMYD2 (unknown origin) using biotinylated GSRAHSSHLKSKKGQSTSRH as substrate assessed as incorporation of tritium labeled methyl group from [3H]-SAM to biotinylated peptide substrate after 40 mins by scintillation proximity assay | Homo sapiens | 11 | single protein format | Scientific Literature | ||
| 13. | ALA3592283 | B | Competitive inhibition of SMYD2 (unknown origin) after 40 mins by scintillation proximity assay in presence of biotinylated GSRAHSSHLKSKKGQSTSRH substrate | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 14. | ALA3592284 | B | Uncompetitive inhibition of SMYD2 (unknown origin) after 40 mins by scintillation proximity assay in presence of SAM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 15. | ALA3592986 | B | Inhibition of SMYD2 in human A549 cells assessed as reduction of p53K370me1 to overall p53 ratio at 10 uM after 18 hrs | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 16. | ALA3592989 | B | Inhibition of SMYD2 in human A549 cells assessed as reduction of p53K370me1 level at 10 uM after 18 hrs relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA3592990 | B | Inhibition of recombinant full-length human SMYD2 (1 to 433) expressed in Escherichia coli BL21Star(DE3) cells using p53 peptide as substrate after 90 mins by scintillation proximity assay in presence of [3H]-SAM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA3592997 | B | Inhibition of SMYD2 (unknown origin) using p53 (361 to 380) as substrate assessed as incorporation of tritium labeled methyl group from [3H]-SAM to p53 peptide substrate after 1 hr by scintillation proximity assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 19. | ALA3784098 | B | Inhibition of human SYMD2 at 10 and 50 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 20. | ALA3803388 | B | Inhibition of SMYD2 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature |
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