| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2175720 | B | Ratio of BM15.766 IC50 to compound IC50 for 7-dehydroxycholesterol reductase-mediated cholesterol biosynthesis in human HL60 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA2175827 | B | Inhibition of 7-dehydroxycholesterol reductase-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate after 24 hrs GC/MS analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 3. | ALA2175830 | B | Inhibition of 7-dehydrocholesterol reductase in human HL60 cells assessed as accumulation of 7-dehydrocholesterol at 50 uM after 24 hrs by GC/MS analysis | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 4. | ALA2175831 | B | Inhibition of 7-dehydrocholesterol reductase in human HL60 cells assessed as accumulation of 7-dehydrocholesterol at 1 uM after 24 hrs by GC/MS analysis | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 5. | ALA3541199 | B | Inhibition of DHCR7 activity in human hepatocytes assessed as increase in 7-dehydrocholesterol level per gram of protein by GC-MS analysis (Rvb = 16.3 ug) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA3767661 | B | Inhibition of 7-dehydrocholesterol reductase in human HL60 cells assessed as accumulation of 7-dehydrocholesterol by GC-MS method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA5226846 | B | Inhibition of DHCR7 (unknown origin) | Homo sapiens | 7 | single protein format | Scientific Literature |
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