# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2174998 | B | Inhibition of recombinant Tdp2 | 1 | single protein format | Scientific Literature | |||
2. | ALA2423452 | B | Inhibition of TDP2 (unknown origin) using 5'-Y-TCCGTTGAAGCCTGCTTT-3' as substrate after 60 mins | Homo sapiens | 22 | single protein format | Scientific Literature | ||
3. | ALA2423455 | B | Inhibition of TDP2 (unknown origin) using 4-nitrophenyl phenylphosphonate as substrate at 50 uM after 60 mins relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
4. | ALA2423457 | B | Inhibition of TDP2 (unknown origin) using 4-nitrophenyl phenylphosphonate as substrate at 30 uM after 60 mins relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
5. | ALA2423658 | B | Inhibition of TDP2 (unknown origin) using 4-nitrophenyl phenylphosphonate as substrate after 60 mins | Homo sapiens | 88 | single protein format | Scientific Literature | ||
6. | ALA3215006 | B | PubChem BioAssay. Epi Absorbance-based biochemical high throughput dose response assay to identify inhibitors of human tyrosyl-DNA phosphodiesterase 2 (TDP2). (Class of assay: confirmatory) | 221 | single protein format | PubChem BioAssays | |||
7. | ALA3585166 | B | Inhibition of human recombinant TPD2 activity using 5'phosphotyrosine-containing 19-mer single-stranded oligonucleotide DNA substrate by PAGE assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
8. | ALA3767499 | B | Inhibition of recombinant human TDP2 using alpha32P-cordycepin-30-labeled 19-mer single-stranded oligonucleotide DNA containing 5'-phosphotyrosine (Y19) for 15 mins by PAGE assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
9. | ALA3796252 | B | Inhibition of recombinant human TDP2 using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay | Homo sapiens | 64 | single protein format | Scientific Literature | ||
10. | ALA3796255 | B | Inhibition of human TDP2 expressed in DT40 cells (TDP2-knockout) using 18-mer single stranded oligonucleotide DNA as substrate incubated for 15 mins by PAGE assay | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
11. | ALA3812293 | B | Inhibition of human recombinant TDP2 using 19-mer single stranded DNA containing 5'-phosphotyrosine as substrate after 15 mins by PAGE | Homo sapiens | 20 | single protein format | Scientific Literature | ||
12. | ALA3816823 | B | Inhibition of human TDP2 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
13. | ALA3816824 | B | Inhibition of human recombinant TDP2 using alpha32P-cordycepin-3'-labeled TY19 as substrate after 15 mins by PAGE method | Homo sapiens | 3 | single protein format | Scientific Literature | ||
14. | ALA3816828 | B | Inhibition of endogenous human TDP2 within whole cell extracts from human TDP2-complemented DT40 chicken cells using TY19 DNA as substrate after 15 mins by spectrophotometric analysis | Homo sapiens | 3 | assay format | Scientific Literature | ||
15. | ALA3816829 | B | Inhibition of human recombinant TDP2 using alpha32P-cordycepin-3'-labeled TY19 as substrate at 0.46 to 111 uM after 15 mins in presence of DTT by PAGE method | Homo sapiens | 2 | single protein format | Scientific Literature | ||
16. | ALA3816830 | B | Inhibition of human recombinant TDP2 using alpha32P-cordycepin-3'-labeled TY19 as substrate at 0.46 to 111 uM after 15 mins in absence of DTT by PAGE method | Homo sapiens | 2 | single protein format | Scientific Literature | ||
17. | ALA4011567 | B | Inhibition of recombinant human Tdp2 assessed as decrease in alpha 32P-cordycepin-3'-labeled DNA breaks after 15 mins by PAGE analysis | Homo sapiens | 13 | single protein format | Scientific Literature | ||
18. | ALA4040007 | B | Inhibition of recombinant human TDP2 using 3'-labeled alpha-[32P]-cordycepin as substrate after 15 mins | Homo sapiens | 20 | single protein format | Scientific Literature | ||
19. | ALA4153697 | B | Inhibition of recombinant human TDP2 using TY18 (alpha-[32P]-cordycepin-3'-labeled) as substrate after 15 mins by PAGE analysis | Homo sapiens | 74 | single protein format | Scientific Literature | ||
20. | ALA4153698 | B | Inhibition of human TDP2 expressed in TDP2 deficient chicken DT40 whole cell extracts using TY19 DNA as substrate after 15 mins by by PAGE analysis | Homo sapiens | 73 | assay format | Scientific Literature |