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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA666530 Functional Effective concentration to inhibit D216,ND217N,E218Q KL-2 Opioid receptor kappa 1 binding to [35S]GTP-gamma-S, expressed in COS cells 1 ALA1132988 cell-based format Scientific Literature 2. ALA666531 Binding Dissociation constant against D216N,D217N,E218Q EL-2 Opioid receptor kappa 1 expressed in HEK cells 1 ALA1132988 cell-based format Scientific Literature 3. ALA663515 Binding Binding constant against D216N,D217N,E218Q EL-2 Opioid receptor kappa 1 using [3H]diprenorphine as radioligand expressed in HEK cells 2 ALA1132988 cell-based format Scientific Literature 4. ALA679838 Binding Dissociation constant against E203Q,D204N,D206N EL-2 Opioid receptor kappa 1 expressed in HEK cells 1 ALA1132988 cell-based format Scientific Literature 5. ALA679839 Binding Binding constant against E203Q,D204N,D206N EL-2 Opioid receptor kappa 1 using [3H]diprenorphine as radioligand expressed in HEK cells 2 ALA1132988 cell-based format Scientific Literature 6. ALA679840 Functional Effective concentration to inhibit E203Q,D204N,D206N KL-2 Opioid receptor kappa 1 binding to [35S]GTP-gamma-S, expressed in COS cells 1 ALA1132988 cell-based format Scientific Literature 7. ALA679841 Binding Dissociation constant against E203Q,D204N,D206N,E209Q EL-2 Opioid receptor kappa 1 expressed in HEK cells 1 ALA1132988 cell-based format Scientific Literature 8. ALA679842 Binding Binding constant against E203Q,D204N,D206N,E209Q EL-2 Opioid receptor kappa 1 using [3H]diprenorphine as radioligand expressed in HEK cells 2 ALA1132988 cell-based format Scientific Literature 9. ALA677621 Functional Effective concentration to inhibit E203Q,D204N,D206N,E209Q KL-2 Opioid receptor kappa 1 binding to [35S]GTP-gamma-S, expressed in COS cells 1 ALA1132988 cell-based format Scientific Literature 10. ALA700237 Binding Binding affinity against rat kappa-opioid receptor expressed in CHO cells was determined by competitive inhibition of 2 nM [3H]-U 69593 Rattus norvegicus 9 ALA1130911 cell-based format Scientific Literature 11. ALA1062525 Binding Displacement of [3H]Diprenorphine from rat kappa opioid receptor expressed in CHO cells Rattus norvegicus 7 ALA1153526 cell-based format Scientific Literature 12. ALA1062530 Functional Agonist activity at rat cloned kappa opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production by scintillation counting Rattus norvegicus 7 ALA1153526 cell-based format Scientific Literature 13. ALA1062531 Functional Agonist activity at rat cloned kappa opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production by scintillation counting relative to Dyn A-(1-13)NH2 Rattus norvegicus 7 ALA1153526 cell-based format Scientific Literature 14. ALA1058575 Functional Activity at rat kappa opioid receptor expressed in CHO cells assessed as inhibition of adenylyl cyclase activity at 10 uM relative to Dyn A-(1-13)NH2 Rattus norvegicus 11 ALA1154596 cell-based format Scientific Literature 15. ALA1058576 Functional Activity at rat kappa opioid receptor expressed in CHO cells assessed as inhibition of adenylyl cyclase activity Rattus norvegicus 1 ALA1154596 cell-based format Scientific Literature 16. ALA1058577 Binding Displacement of [3H]diprenorphine from rat kappa opioid receptor expressed in CHO cells Rattus norvegicus 16 ALA1154596 cell-based format Scientific Literature 17. ALA1049574 Binding Displacement of [3H]U69593 from rat kappa opioid receptor expressed in HEK293 cells by liquid scintillation counting Rattus norvegicus 11 ALA1152515 cell-based format Scientific Literature 18. ALA1049577 Binding Displacement of [3H]bremazocine from rat kappa opioid receptor expressed in HEK293 cells by liquid scintillation counting Rattus norvegicus 2 ALA1152515 cell-based format Scientific Literature 19. ALA753141 Binding Binding ability towards opioid receptor kappa expressed in homogenates of rat brain. 9 ALA1126138 tissue-based format Scientific Literature 20. ALA753142 Binding The compound was tested for the ability to displace opioid receptor kappa specific radioligand [3H]DADLE 4 ALA1124680 single protein format Scientific Literature