# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3427827 | Binding | Inhibition of CHK2 (unknown origin) assessed as remaining activity at 100 uM by radioactive filter binding assay in presence of [33P]-ATP relative to control | Homo sapiens | 16 | ALA3425453 | single protein format | Scientific Literature | |
2. | ALA3430801 | Binding | Delta TM value showing the stabilisation of CHEK2 produced by compound binding | Homo sapiens | 156 | ALA1145498 | single protein format | Scientific Literature | |
3. | ALA3595497 | Binding | Inhibition of human CHK2 at 0.1 uM relative to control | Homo sapiens | 1 | ALA3593229 | single protein format | Scientific Literature | |
4. | ALA3606971 | Binding | Inhibition of CHK2 (unknown origin) at 250 nM by radioactive filter-binding assay | Homo sapiens | 1 | ALA3603808 | single protein format | Scientific Literature | |
5. | ALA3632311 | Binding | Inhibition of CHK2 (unknown origin) at 10 uM after 120 mins P33 radiolabeled kinase activity assay | Homo sapiens | 3 | ALA3627608 | single protein format | Scientific Literature | |
6. | ALA3734466 | Binding | Inhibition of recombinant human CHK2 using fluorescein-labeled peptide as substrate by fluorescence-electrophoretic mobility shift assay | Homo sapiens | 1 | ALA3727354 | single protein format | Patent Bioactivity Data | |
7. | ALA3737351 | Binding | Inhibition of CHEK2 (unknown origin) at 1 uM by selectscreen kinase profiling assay in presence of ATP | Homo sapiens | 1 | ALA3734692 | single protein format | Scientific Literature | |
8. | ALA3743119 | Binding | Inhibition of CHK2 (unknown origin) at 30 uM by microfluidic assay relative to control | Homo sapiens | 19 | ALA3739348 | single protein format | Scientific Literature | |
9. | ALA3743720 | Binding | Inhibition of CHK2 (unknown origin) | Homo sapiens | 1 | ALA3739276 | single protein format | Scientific Literature | |
10. | ALA3751064 | Binding | Inhibition of CHK2 (unknown origin) at 1 uM | Homo sapiens | 1 | ALA3745631 | single protein format | Scientific Literature | |
11. | ALA3748671 | Binding | Inhibition of human CHK2 using [KKKVSRSGLYRSPSMPENLNRPR] as substrate | Homo sapiens | 1 | ALA3745707 | single protein format | Scientific Literature | |
12. | ALA3762304 | Binding | Inhibition of CHK2 (unknown origin) at 100 nM | Homo sapiens | 1 | ALA3758169 | single protein format | Scientific Literature | |
13. | ALA3767168 | Binding | Inhibition of CHK2 (unknown origin) at 10 uM | Homo sapiens | 1 | ALA3763027 | single protein format | Scientific Literature | |
14. | ALA3777420 | Binding | Inhibition of recombinant CHK2 (unknown origin) assessed as residual activity at 1 uM relative to control | Homo sapiens | 1 | ALA3774312 | single protein format | Scientific Literature | |
15. | ALA3776411 | Binding | Inhibition of human CHK2 (5 to 543 residues) at 1 uM by radioactive [33P]-ATP filter binding assay | Homo sapiens | 1 | ALA3774338 | single protein format | Scientific Literature | |
16. | ALA3776911 | Binding | Inhibition of N-terminal His6-tagged recombinant human CHK2 expressed in baculovirus infected insect Sf9 cells assessed as remaining activity at 1 uM relative to control | Homo sapiens | 3 | ALA3774357 | cell-based format | Scientific Literature | |
17. | ALA3776912 | Binding | Inhibition of N-terminal His6-tagged recombinant human CHK2 I157T mutant expressed in baculovirus infected insect Sf9 cells assessed as remaining activity at 1 uM relative to control | Homo sapiens | 3 | ALA3774357 | cell-based format | Scientific Literature | |
18. | ALA3777128 | Binding | Inhibition of N-terminal His6-tagged recombinant human CHK2 R145W expressed in baculovirus infected insect Sf9 cells assessed as remaining activity at 1 uM relative to control | Homo sapiens | 3 | ALA3774357 | cell-based format | Scientific Literature | |
19. | ALA3789286 | Binding | Inhibition of human CHK2 at 1 uM after 30 mins by fluorescence assay in presence of ATP | Homo sapiens | 1 | ALA3784918 | single protein format | Scientific Literature | |
20. | ALA3802093 | Binding | Inhibition of CHK2 (unknown origin) at 1 uM | Homo sapiens | 4 | ALA3797078 | single protein format | Scientific Literature |