| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2185107 | B | Activity of spermine oxidase in human DU145 cells assessed per ug DNA at 100 uM after 72 hrs in presence of serum amine oxidase inhibitor aminoguanidine (RVb = 742 +/- 10 pmol/h per ug DNA) | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 2. | ALA2185108 | B | Activity of spermine oxidase in human DU145 cells assessed per ug DNA at 100 uM after 48 hrs in presence of serum amine oxidase inhibitor aminoguanidine (RVb = 680 +/- 29 pmol/h per ug DNA) | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 3. | ALA2185109 | B | Activity of spermine oxidase in human DU145 cells assessed per ug DNA at 100 uM after 24 hrs in presence of serum amine oxidase inhibitor aminoguanidine (RVb = 493 +/- 22 pmol/h per ug DNA) | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 4. | ALA4324839 | A | Substrate activity at recombinant human SMOX at 1 mM | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 5. | ALA4324840 | A | Substrate activity at recombinant human SMOX assessed as Vmax at 2000 to 6000 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 6. | ALA4324841 | A | Substrate activity at recombinant human SMOX assessed as Km at 2000 to 6000 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA4324844 | B | Inhibition of recombinant human SMOX at 50 uM using spermine as substrate relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA4324845 | B | Inhibition of recombinant human SMOX at 500 uM using spermine as substrate relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA4373779 | B | Inhibition of SMOX (unknown origin) assessed as decrease in spermidine formation using spermine as substrate at 10 uM treated with compound 2 mins prior to substrate addition followed by further incubation for 1 hr by HPLC analysis relative to control | Homo sapiens | 16 | single protein format | Scientific Literature | ||
| 10. | ALA4373780 | B | Inhibition of SMOX (unknown origin) assessed as decrease in spermidine formation using spermine as substrate treated with compound 2 mins prior to substrate addition followed by further incubation for 1 hr by HPLC analysis | Homo sapiens | 15 | single protein format | Scientific Literature | ||
| 11. | ALA4373787 | B | Potency index, ratio of MDL72527 IC50 to compound IC50 for SMOX (unknown origin) using spermine as substrate treated with compound 2 mins prior to substrate addition followed by further incubation for 1 hr by HPLC analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 12. | ALA4716981 | B | Inhibition of recombinant human SMOX | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 13. | ALA5059547 | B | HyPerBlu SMOX enzymatic assay | Homo sapiens | 2 | single protein format | Donated Chemical Probes - SGC Frankfurt | ||
| 14. | ALA5059548 | B | Horseradish Peroxidase (HRP) Fluorescence Assay | Homo sapiens | 1 | single protein format | Donated Chemical Probes - SGC Frankfurt | ||
| 15. | ALA5059549 | B | SMOX CETSA assay | Homo sapiens | 1 | single protein format | Donated Chemical Probes - SGC Frankfurt | ||
| 16. | ALA5248769 | B | Inhibition of SMOX (unknown origin) at 50 uM using spermine as substrate preincubated for 1 hr followed by substrate addition and measured after 20 mins by luminometer analysis relative to control | Homo sapiens | 1 | single protein format | Scientific Literature |
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