| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2187441 | B | Binding affinity at human recombinant ARTD7 expressed in Escherichia coli BL21 (DE3) R3 pRARE cells assessed as thermal stability shift by differential scanning fluorimetry | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 2. | ALA2433127 | B | Inhibition of human ARTD7 (460 to 656) using NAD+ as substrate at 1 uM by fluorescence assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 3. | ALA3420115 | B | Inhibition of hexahistidine-tagged human recombinant ARTD7 catalytic domain (459 to 656 amino acids) expressed in Escherichia coli BL21(DE3) assessed as inhibition of ADP-ribosyltransferase activity incubated for 15 mins using biotin-NAD+ by chemiluminescence detection based assay | Homo sapiens | 20 | assay format | Scientific Literature | ||
| 4. | ALA3420119 | B | Inhibition of hexahistidine-tagged human recombinant ARTD7 catalytic domain (459 to 656 amino acids) expressed in Escherichia coli BL21(DE3) assessed as inhibition of ADP-ribosyltransferase activity at 200 uM incubated for 15 mins using biotin-NAD+ by chemiluminescence detection based assay | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 5. | ALA3595285 | B | Inhibition of human ARTD7 (460 to 656) using 250 nM NAD substrate after 2 hrs incubation | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 6. | ALA3595287 | B | Inhibition of human ARTD7 (460 to 656) using 250 nM NAD substrate at 10 uM after 2 hrs incubation | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 7. | ALA3757404 | B | Inhibition of human ARTD7 by fluorescence analysis | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 8. | ALA3995371 | B | Inhibition of recombinant human His6-tagged PARP15 ADP-ribosyltransferase domain expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylated NAD+ addition by chemiluminescence assay | Homo sapiens | 8 | assay format | Scientific Literature | ||
| 9. | ALA4003524 | B | Inhibition of PARP15 (unknown origin) | Homo sapiens | 7 | single protein format | Scientific Literature | ||
| 10. | ALA4022069 | B | Inhibition of His6-tagged PARP15 (unknown origin) preincubated for 15 mins followed by biotinylated NAD+ addition by chemiluminescence assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA4032830 | B | Inhibition of human PARP15 using NAD+ as substrate by fluorescence assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 12. | ALA4122807 | B | Inhibition of full length recombinant His6-tagged PARP15 catalytic domain (unknown origin) expressed in Escherichia coli BL21(DE3) by fluorescence based assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 13. | ALA4272748 | B | Inhibition of N-terminal His-tagged human ARTD7 (482 to 678 residues) expressed in Escherichia coli Rosetta2 (DE3) using SRPK2 as substrate after 3 hrs in presence of NAD+ | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 14. | ALA4311851 | B | Inhibition of human PARP15 catalytic domain assessed as reduction in MARylation of SRPK2 substrate after 60 mins in presence of 6-a-NAD+ by chemifluorescence assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 15. | ALA4322271 | B | Inhibition of human N-terminal GST-tagged PARP15 (221 to 444 residues) expressed in Escherichia coli using biotinylated substrate by chemiluminescence method | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 16. | ALA4380689 | B | Inhibition of PARP15 (unknown origin) using biotin-NAD+, NAD+ and sIDNA as substrate at 5 uM incubated for 1 hr by ELISA relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 17. | ALA4618660 | B | Inhibition of N-terminal His-tagged human ARTD7 (482 to 678 residues) expressed in Escherichia coli Rosetta2 (DE3) using SRPK2 as substrate after 3 hrs in presence of NAD+ | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 18. | ALA4701313 | B | Inhibition of N-terminal GST-tagged human PARP15 (221 to 444 residues) expressed in Escherichia coli assessed as reduction in NAD+-dependent ADP ribosylation using histone as substrate at 10 uM incubated for 1 hr in presence of biotinylated NAD+ and activated DNA by chemiluminescence based microplate reader assay relative to control | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 19. | ALA4742558 | B | Inhibition of N-terminal His-tagged human PARP15 catalytic domain (481 to 678 residues) expressed in Escherichia coli BL21 (DE3) cells up to 100 uM in presence of NAD+ incubated for 2 hrs by M-ELISA plate method | Homo sapiens | 8 | cell-based format | Patent Bioactivity Data | ||
| 20. | ALA5030398 | B | Inhibition of PARP15 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature |
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