| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA754458 | F | The compound was evaluated for antagonist activity against recombinant rat P2X purinoceptor 7 (P2X7) | 2 | ALA1135773 | assay format | Scientific Literature | ||
| 2. | ALA754459 | F | The compound was evaluated for antagonist activity against P2X purinoceptor 7 (P2X7) in rat parotid acinar cells | 1 | ALA1135773 | cell-based format | Scientific Literature | ||
| 3. | ALA872175 | F | Inhibitory concentration against rat P2X purinoceptor 7 expressed in Xenopus laevis oocytes | Rattus norvegicus | 1 | ALA1140384 | cell-based format | Scientific Literature | |
| 4. | ALA869037 | F | Antagonist activity at rat P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of calcium flux by FLIPR | Rattus norvegicus | 10 | ALA1148647 | cell-based format | Scientific Literature | |
| 5. | ALA900721 | F | Antagonist activity at rat P2X7 receptor transfected in HEK cells assessed as inhibition of benzoyl-ATP-induced changes in plasma membrane pore formation | Rattus norvegicus | 20 | ALA1138274 | cell-based format | Scientific Literature | |
| 6. | ALA886456 | F | Antagonist activity at rat recombinant P2X7 receptor | Rattus norvegicus | 5 | ALA1139969 | assay format | Scientific Literature | |
| 7. | ALA932846 | F | Antagonist activity at rat recombinant P2X7 receptor assessed as inhibition of calcium flux by FLIPR assay | Rattus norvegicus | 28 | ALA1143222 | assay format | Scientific Literature | |
| 8. | ALA932853 | F | Antagonist activity at rat recombinant P2X7 receptor assessed as inhibition of BzATP-induced calcium flux by FLIPR assay | Rattus norvegicus | 38 | ALA1143223 | assay format | Scientific Literature | |
| 9. | ALA982857 | F | Antagonist activity at rat recombinant P2X7 receptor assessed as inhibition of BzATP induced calcium flux by FLIPR assay | Rattus norvegicus | 23 | ALA1155124 | assay format | Scientific Literature | |
| 10. | ALA970589 | F | Antagonist activity at rat cloned P2X7 receptor expressed in HEK293 cells assessed as inhibition of calcium flux by FLIPR assay | Rattus norvegicus | 59 | ALA1138502 | cell-based format | Scientific Literature | |
| 11. | ALA964573 | F | Antagonist activity at P2X7R in BzATP-stimulated rat spinal cord assessed as decrease in fluorescent propidium iodide dye uptake at 1 uM | Rattus norvegicus | 6 | ALA1157446 | assay format | Scientific Literature | |
| 12. | ALA958118 | F | Antagonist activity at rat recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assay | Rattus norvegicus | 35 | ALA1150301 | cell-based format | Scientific Literature | |
| 13. | ALA1028698 | B | Activity at rat P2X7 receptor expressed in HEK cells assessed as effect on BzATP-induced ethidium uptake | Rattus norvegicus | 9 | ALA1151820 | cell-based format | Scientific Literature | |
| 14. | ALA1048346 | F | Antagonist activity at rat recombinant P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of agonist-induced calcium flux by fluorometric assay | Rattus norvegicus | 1 | ALA1154101 | cell-based format | Scientific Literature | |
| 15. | ALA1048350 | B | Binding affinity at rat P2X7 receptor | Rattus norvegicus | 1 | ALA1154101 | single protein format | Scientific Literature | |
| 16. | ALA1103861 | B | Inhibition of rat P2X7 receptor assessed as inhibition of ethidium bromide accumulation | Rattus norvegicus | 2 | ALA1157114 | single protein format | Scientific Literature | |
| 17. | ALA1212279 | F | Antagonist activity at rat P2X7 receptor ethidium bromide release assay | Rattus norvegicus | 2 | ALA1208703 | assay format | Scientific Literature | |
| 18. | ALA1228419 | B | Inhibition of rat P2X7 receptor by ethidium bromide release assay | Rattus norvegicus | 6 | ALA1221272 | single protein format | Scientific Literature | |
| 19. | ALA1273100 | F | Antagonist activity at rat recombinant P2X7 receptor | Rattus norvegicus | 3 | ALA1268987 | assay format | Scientific Literature | |
| 20. | ALA1680813 | F | Antagonist activity against rat P2X7 receptor expressed in Xenopus laevis oocyte assessed as inhibition of alpha, beta-meATP-induced inward current by two-electrode voltage-clamp electrophysiology | Rattus norvegicus | 1 | ALA1671813 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!