# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2185357 | B | Binding affinity to human recombinant biotinylated receptor for advanced glycation end product expressed in Escherichia coli DE3 after 1 min by surface plasmon resonance assay | Homo sapiens | 1 | ALA2176979 | assay format | Scientific Literature | |
2. | ALA2185367 | B | Inhibition of human recombinant biotinylated receptor for advanced glycation end product expressed in Escherichia coli DE3 assessed as inhibition of binding to amyloid beta (1 to 42) after 60 mins by TMB-ELISA | Homo sapiens | 2 | ALA2176979 | assay format | Scientific Literature | |
3. | ALA2185368 | B | Inhibition of human recombinant biotinylated receptor for advanced glycation end product expressed in Escherichia coli DE3 assessed as inhibition of binding to amyloid beta (1 to 42) at 20 uM after 60 mins by TMB-ELISA | Homo sapiens | 39 | ALA2176979 | assay format | Scientific Literature | |
4. | ALA2210067 | F | Antagonist activity at RAGE transfected in CHO cells assessed as inhibition of amyloid beta 42-induced NFkappaB activation at 1 uM after 18 hrs by luciferase reporter gene assay | 10 | ALA2203145 | cell-based format | Scientific Literature | ||
5. | ALA2210069 | B | Antagonist activity at human biotinylated RAGE assessed as inhibition of amyloid beta binding after 60 mins by ELISA | Homo sapiens | 15 | ALA2203145 | single protein format | Scientific Literature | |
6. | ALA2210070 | B | Antagonist activity at human biotinylated RAGE assessed as inhibition of amyloid beta binding at 10 uM after 60 mins by ELISA | Homo sapiens | 24 | ALA2203145 | single protein format | Scientific Literature | |
7. | ALA3243664 | B | Inhibition of biotinylated human RAGE assessed as bound amyloid beta level at 20 uM after 60 mins by ELISA relative to control | Homo sapiens | 27 | ALA3232933 | single protein format | Scientific Literature | |
8. | ALA3243665 | B | Inhibition of biotinylated human RAGE assessed as bound amyloid beta level after 60 mins by ELISA | Homo sapiens | 20 | ALA3232933 | single protein format | Scientific Literature | |
9. | ALA3243666 | B | Binding affinity to biotinylated human RAGE by surface plasmon resonance analysis | Homo sapiens | 1 | ALA3232933 | single protein format | Scientific Literature | |
10. | ALA3395803 | B | Inhibition of biotinylated human RAGE assessed as bound amyloid beta level at 20 uM after 60 mins by ELISA relative to control | Homo sapiens | 23 | ALA3393050 | single protein format | Scientific Literature | |
11. | ALA3595792 | B | Inhibition of human RAGE-amyloid beta-42 interaction at 4 uM preincubated for 30 mins measured after 1 hr by FRET assay relative to control | Homo sapiens | 56 | ALA3593222 | single protein format | Scientific Literature | |
12. | ALA4030321 | B | Binding affinity to human C-terminal His-tagged RAGE domain V (24 to 125 residues) expressed in Escherichia coli BL21(DE3) by tryptophan fluorescence assay | Homo sapiens | 1 | ALA4028844 | assay format | Scientific Literature | |
13. | ALA4030323 | B | Binding affinity to human His-tagged RAGE domain VC1 expressed in Escherichia coli by fluorescence titration method | Homo sapiens | 1 | ALA4028844 | assay format | Scientific Literature | |
14. | ALA4030324 | B | Inhibition of amyloid beta (1 to 42) binding to RAGE domain V (unknown origin) by fluorescence polarization assay | Homo sapiens | 1 | ALA4028844 | single protein format | Scientific Literature | |
15. | ALA4030325 | B | Inhibition of amyloid beta binding to biotin-labeled human RAGE domain V after 60 mins by ELISA | Homo sapiens | 2 | ALA4028844 | single protein format | Scientific Literature | |
16. | ALA4030327 | B | Inhibition of amyloid beta binding to biotin-labeled human RAGE domain V at 20 uM after 60 mins by ELISA relative to cotrol | Homo sapiens | 1 | ALA4028844 | single protein format | Scientific Literature | |
17. | ALA4030328 | B | Displacement of [I125]amyloid beta (1 to 40) from human RAGE domain V expressed in CHO cells | Homo sapiens | 1 | ALA4028844 | cell-based format | Scientific Literature | |
18. | ALA4030329 | B | Inhibition of S110B binding to RAGE (unknown origin) by ELISA | Homo sapiens | 3 | ALA4028844 | single protein format | Scientific Literature | |
19. | ALA4030330 | B | Binding affinity to human RAGE domain V by autoradiography | Homo sapiens | 1 | ALA4028844 | single protein format | Scientific Literature | |
20. | ALA4030331 | B | Inhibition of amyloid beta binding to human RAGE domain V (Met1 to Ala 344 residues) expressed in HEK293 cells after 10 mins by MST assay | Homo sapiens | 1 | ALA4028844 | cell-based format | Scientific Literature |