| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2185435 | B | Displacement of biotinylated-TM PAA from human DC-SIGNR at 50 mM after 3 hrs by colorimetry | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 2. | ALA2185445 | B | Displacement of biotinylated-TM PAA from human DC-SIGNR at 1 mM after 3 hrs by colorimetry | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 3. | ALA5033559 | B | Inhibition of DC-SIGN extracellular domain (unknown origin) binding to HIV gp120 by surface plasmon resonance analysis | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 4. | ALA5033560 | B | Inhibition of full-length DC-SIGN (unknown origin) expressed in human monocyte derived dendritic cells assessed as inhibition of binding to recombinant HCMV gB using flow cytometry | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 5. | ALA5033563 | B | Inhibition of DC-SIGN (unknown origin) expressed in human Jurkat cells assessed as inhibition of EBOV-pseudotyped virus infection measured after 48 hrs by luciferase assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 6. | ALA5033564 | B | Relative inhibitory potency, ratio of alpha-D-mannoside IC50 to test compound IC50 for inhibition of DC-SIGN (unknown origin) expressed in human Jurkat cells assessed as inhibition of EBOV-pseudotyped virus infection measured after 48 hrs by luciferase assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA5114289 | B | Inhibition of DC-SIGN (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 8. | ALA5136433 | B | Binding affinity to N-terminal His-tagged DC-SIGN CRD (194 to 331 residues) (unknown origin) expressed in Escherichia coli BL21 assessed as dissociation constant by HSQC-NMR spectrum analysis | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 9. | ALA5136434 | B | Binding affinity to DC-SIGN ECD (66 to 404 residue) (unknown origin) expressed in Escherichia coli BL21 assessed as dissociation constant by STD reporter assay based NMR spectroscopy analysis | Homo sapiens | 26 | assay format | Scientific Literature | ||
| 10. | ALA5136435 | B | Displacement of 6-Fluoro-N,N-dimethyl-4-oxo-1,4-dihydroquinoline-3-carboxamide from DC-SIGN ECD (66 to 404 residues) (unknown origin) expressed in Escherichia coli BL21 by STD reporter assay based NMR spectroscopy analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 11. | ALA5136436 | B | Binding affinity to DC-SIGN ECD (66 to 404 residue) (unknown origin) expressed in Escherichia coli BL21 assessed as fold increase by STD reporter assay based NMR spectroscopy analysis | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 12. | ALA5233383 | B | Inhibition of DC-SIGN (unknown origin) by SPR competition binding assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 13. | ALA5233384 | B | Inhibition of DC-SIGN (unknown origin) by solid-phase fluorescence assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 14. | ALA5233386 | B | Inhibition of DC-SIGN (unknown origin) by SPR direct assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 15. | ALA5233387 | B | Inhibition of DC-SIGN (unknown origin) by ITC assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 16. | ALA5233390 | B | Inhibition of DC-SIGN (unknown origin) | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 17. | ALA5233391 | B | Inhibition of DC-SIGN (unknown origin) by high-throughput ELLA-type assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 18. | ALA5233392 | B | Inhibition of fluorescent labeled mannosylated BSA probe to DC-SIGN (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 19. | ALA5233393 | B | Inhibition of DC-SIGN (unknown origin)- mediated fluorescent probe binding at 0.1 mM relative to control | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 20. | ALA5233394 | B | Inhibition of DC-SIGN (unknown origin)- mediated fluorescent probe binding at 1 mM relative to control | Homo sapiens | 2 | single protein format | Scientific Literature |
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