# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2209050 | B | Ratio of IC50 for EZH2-mediated proliferation of human LNCaP cells to IC50 for EZH2-mediated nuclear H3K27 methylation in human HCC1806 cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
2. | ALA2209069 | B | Inhibition of EZH2-mediated proliferation of human LNCaP cells after 6 days by chemiluminescence analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
3. | ALA2209070 | B | Inhibition of EZH2-mediated proliferation of human PC3 cells after 6 days by chemiluminescence analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
4. | ALA2209071 | B | Inhibition of EZH2-mediated proliferation of human DU145 cells after 6 days by chemiluminescence analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
5. | ALA2209072 | B | Inhibition of EZH2-mediated proliferation of human ZR-75-1 cells after 6 days by chemiluminescence analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
6. | ALA2209073 | B | Inhibition of EZH2-mediated proliferation of human SKBR3 cells after 6 days by chemiluminescence analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
7. | ALA2209074 | B | Inhibition of EZH2-mediated proliferation of human HCC180 cells after 6 days by chemiluminescence analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
8. | ALA2209075 | B | Inhibition of EZH2-mediated nuclear H3K27 methylation in human HCC1806 cells at >1000 nM after 72 hrs by immunofluorescence analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
9. | ALA2209076 | B | Inhibition of EZH2-mediated nuclear H3K27 methylation in human HCC1806 cells after 72 hrs by immunofluorescence analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
10. | ALA5138958 | B | Inhibition of recombinant human EZH2 (2 to 746 residues) at 1 to 10 uM incubated for 60 mins in presence of [3H]-SAM by hotspot assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
11. | ALA3134968 | B | Inhibition of EZH2 (unknown origin) using [methyl-3H]SAM and biotinylated nucleosome PRC2 and H3K27Me3 activator peptide up to 80 uM by [3H]methyl group incorporation assay | Homo sapiens | 30 | single protein format | Scientific Literature | ||
12. | ALA3271451 | B | Inhibition of wild type EZH2 (unknown origin) | Homo sapiens | 47 | single protein format | Scientific Literature | ||
13. | ALA3271452 | B | Inhibition of EZH2 Y641N mutant (unknown origin) | Homo sapiens | 13 | assay format | Scientific Literature | ||
14. | ALA3271456 | B | Inhibition of EZH2 in human HeLa cells assessed as reduction in H3K27me3 level | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
15. | ALA3271462 | B | Inhibition of EZH2 in human KARPAS422 cells assessed as global reduction in H3K27me3 level by ELISA-based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
16. | ALA3271463 | B | Inhibition of EZH2 in human KARPAS422 cells assessed as global reduction in H3K27me3 level after 4 days by ELISA-based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
17. | ALA3271464 | B | Inhibition of EZH2 in human KARPAS422 cells assessed as global reduction in H3K27me3 level after 7 days by ELISA-based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
18. | ALA3271465 | B | Inhibition of EZH2 in human KARPAS422 cells assessed as global reduction in H3K27me3 level after 10 days by ELISA-based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
19. | ALA3292507 | B | Inhibition of EZH2 histone methyltransferase in human pfeiffer cells assessed as inhibition of H3K27me3 methylation at 1 to 3 uM after 72 hrs by ELISA | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
20. | ALA3292508 | B | Inhibition of EZH2 histone methyltransferase in human pfeiffer cells assessed as inhibition of H3K27me3 methylation after 48 hrs by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |