| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3399058 | B | Inhibition of EZH1 (unknown origin) by HMT assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 2. | ALA3399148 | B | Ratio of S-adenosyl-L-homocysteine IC50 to compound IC50 for EZH1 (unknown origin) by HMT assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 3. | ALA3592401 | B | Inhibition of EZH1 pentameric complex (unknown origin) assessed as incorporation of tritium labeled methyl group from [3H]-SAM to substrate at 1 uM after 1 hr by scintillation proximity assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 4. | ALA3803124 | B | Inhibition of EZH1 (unknown origin) at 10 uM relative to control | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 5. | ALA3871092 | B | Inhibition of human EZH1 complex using histone H3 as substrate after 1 hr in presence of 3H-SAM by filter paper detection analysis | Homo sapiens | 11 | single protein format | Scientific Literature | ||
| 6. | ALA4027425 | B | Binding affinity to EZH1 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA4195597 | B | Inhibition of recombinant human N-terminal His-tagged EZH1 (2 to end residues) expressed in baculovirus infected Sf9 cells at 10 uM relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 8. | ALA4479463 | B | Inhibition of EZH1 histone methyltransferase activity of EZH1/EED/SUZ12/RBBP4/AEBP2 protein complex (unknown origin) using histone H3 peptide as substrate (21 to 44 residues) in presence of [3H]-S-adenosylmethionine after 2 hrs by scintillation proximity assay | Homo sapiens | 54 | single protein format | Scientific Literature | ||
| 9. | ALA4628255 | B | Inhibition of Ezh1 (unknown origin) preincubated for 15 mins followed by addition of substrate measured after 1 hr by AlphaLISA assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA4735337 | B | Inhibition of EZH1 in PRC2 complex (unknown origin) using biotinylated peptide as substrate in presence of S-adenosylmethionine | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA4766109 | B | Inhibition of EZH1 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 12. | ALA4833670 | B | Inhibition of EZH1 (unknown origin) at 10 uM using SAM as substrate measured up to 960 mins by AlphaScreen microplate reader assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 13. | ALA5039144 | B | Inhibition of recombinant full length human N-terminal FLAG-tagged EZH1 in PRC2 complex expressed in baculovirus system using SAM as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins by AlphaLISA immunodetection assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 14. | ALA5109075 | B | Inhibition of EZH1 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 15. | ALA5119830 | B | Inhibition of human recombinant N-terminal FLAG-tagged EZH1 (2 to 747 residues) expressed in insect cell/baculovirus expression system at 10 uM in presence of [3H]-SAM by scintillation/filter plate assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 16. | ALA5119867 | B | Inhibition of human recombinant N-terminal FLAG-tagged EZH1 (2 to 747 residues) expressed in insect cell/baculovirus expression system at 50 uM in presence of [3H]-SAM by scintillation/filter plate assay relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 17. | ALA5123946 | B | Inhibition of wild-type EZH1 (unknown origin) by AlphaLisa assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 18. | ALA5123952 | B | Inhibition of EZH1 (unknown origin) by AlphaLisa assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 19. | ALA5123956 | B | Inhibition of EZH1 (unknown origin) | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 20. | ALA5123963 | B | Displacement of [3H]-SAM from EZH1 (unknown origin) using histone H3 as substrate incubated for 2 hrs by cell-free assay | Homo sapiens | 1 | single protein format | Scientific Literature |
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