| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3382328 | B | Displacement of FITC-labeled EZH2 peptide from recombinant N-terminal 6His-tagged EED (residues 81 to 441) (unknown origin) expressed in Escherichia coli strain BL21 (DE3) after 1 hr by fluorescence polarization assay | Homo sapiens | 1 | ALA3351265 | assay format | Scientific Literature | |
| 2. | ALA3382329 | B | Stabilization of recombinant N-terminal 6His-tagged EED (residues 81 to 441) (unknown origin) expressed in Escherichia coli strain BL21 (DE3) at 1:250 EED:compound ratio using SYPRO orange by thermal shift assay | Homo sapiens | 1 | ALA3351265 | assay format | Scientific Literature | |
| 3. | ALA3382330 | B | Stabilization of recombinant N-terminal 6His-tagged EED (residues 81 to 441) (unknown origin) expressed in Escherichia coli strain BL21 (DE3) at 1:200 EED:compound ratio using SYPRO orange by thermal shift assay | Homo sapiens | 1 | ALA3351265 | assay format | Scientific Literature | |
| 4. | ALA3382331 | B | Stabilization of recombinant N-terminal 6His-tagged EED (residues 81 to 441) (unknown origin) expressed in Escherichia coli strain BL21 (DE3) at 1:100 EED:compound ratio using SYPRO orange by thermal shift assay | Homo sapiens | 1 | ALA3351265 | assay format | Scientific Literature | |
| 5. | ALA3382332 | B | Stabilization of recombinant N-terminal 6His-tagged EED (residues 81 to 441) (unknown origin) expressed in Escherichia coli strain BL21 (DE3) at 1:50 EED:compound ratio using SYPRO orange by thermal shift assay | Homo sapiens | 1 | ALA3351265 | assay format | Scientific Literature | |
| 6. | ALA3382333 | B | Stabilization of recombinant N-terminal 6His-tagged EED (residues 81 to 441) (unknown origin) expressed in Escherichia coli strain BL21 (DE3) at 1:25 EED:compound ratio using SYPRO orange by thermal shift assay | Homo sapiens | 1 | ALA3351265 | assay format | Scientific Literature | |
| 7. | ALA3384217 | B | Binding affinity to recombinant N-terminal 6His-tagged EED (residues 81 to 441) (unknown origin) expressed in Escherichia coli strain BL21 (DE3) by T1rho NMR spectroscopy | Homo sapiens | 1 | ALA3351265 | assay format | Scientific Literature | |
| 8. | ALA3384218 | B | Binding affinity to recombinant N-terminal 6His-tagged EED (residues 81 to 441) (unknown origin) expressed in Escherichia coli strain BL21 (DE3) by STD NMR spectroscopy | Homo sapiens | 1 | ALA3351265 | assay format | Scientific Literature | |
| 9. | ALA3384219 | B | Stabilization of recombinant N-terminal 6His-tagged EED (residues 81 to 441) (unknown origin) expressed in Escherichia coli strain BL21 (DE3) using SYPRO orange by thermal shift assay | Homo sapiens | 1 | ALA3351265 | assay format | Scientific Literature | |
| 10. | ALA3384846 | B | Stabilization of 2 uM recombinant EED V112E mutant (unknown origin) at 200 uM using SYPRO orange by thermal shift assay in presence of 5 % DMSO | Homo sapiens | 1 | ALA3351265 | single protein format | Scientific Literature | |
| 11. | ALA3384847 | B | Stabilization of 2 uM recombinant EED L123E mutant (unknown origin) at 200 uM using SYPRO orange by thermal shift assay in presence of 5 % DMSO | Homo sapiens | 1 | ALA3351265 | single protein format | Scientific Literature | |
| 12. | ALA3384848 | B | Stabilization of 2 uM recombinant EED L246E mutant (unknown origin) at 200 uM using SYPRO orange by thermal shift assay in presence of 5 % DMSO | Homo sapiens | 1 | ALA3351265 | single protein format | Scientific Literature | |
| 13. | ALA3384849 | B | Stabilization of 2 uM recombinant EED L315D mutant (unknown origin) at 200 uM using SYPRO orange by thermal shift assay in presence of 5 % DMSO | Homo sapiens | 1 | ALA3351265 | single protein format | Scientific Literature | |
| 14. | ALA3384850 | B | Stabilization of 2 uM recombinant EED L353A mutant (unknown origin) at 200 uM using SYPRO orange by thermal shift assay in presence of 5 % DMSO | Homo sapiens | 1 | ALA3351265 | single protein format | Scientific Literature | |
| 15. | ALA3384851 | B | Stabilization of 2 uM recombinant EED F356Y mutant (unknown origin) at 200 uM using SYPRO orange by thermal shift assay in presence of 5 % DMSO | Homo sapiens | 1 | ALA3351265 | single protein format | Scientific Literature | |
| 16. | ALA3859087 | B | Binding affinity to EED (unknown origin) at 200 uM by DSF assay | Homo sapiens | 1 | ALA3856251 | single protein format | Scientific Literature | |
| 17. | ALA3994543 | B | Inhibition of pyrrolidine inhibitor-based oregon-green probe binding to GST-tagged EED (unknown origin) after 1 hr by assay explorer integrated LanthaScreen TR-FRET assay | Homo sapiens | 48 | ALA3992570 | single protein format | Scientific Literature | |
| 18. | ALA3994544 | B | Inhibition of pyrrolidine inhibitor-based oregon-green probe binding to GST-tagged EED (unknown origin) after 1 hr by LanthaScreen TR-FRET assay | Homo sapiens | 47 | ALA3992570 | single protein format | Scientific Literature | |
| 19. | ALA4007108 | B | Inhibition of OG(488) labeled probe binding to GST-tagged EED (unknown origin) after 1 hr by LanthaScreen TR-FRET assay | Homo sapiens | 38 | ALA4004873 | single protein format | Scientific Literature | |
| 20. | ALA4007109 | B | Inhibition of EED in human G401 cells assessed as reduction in H3K27 trymethylation measured after 6 days by alphaLISA method | Homo sapiens | 9 | ALA4004873 | cell-based format | Scientific Literature |
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