| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2209081 | B | Inhibition of ABHD6 binding to FP-biotin in [12C][14N]-lysine, arginine and [13C6][15N2]-lysine, arginine labeled HEK293T cells at 20 uM after 1 hr by isotopic activity-based protein profiling-MudPIT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA3089725 | B | Inhibition of human ABHD6 overexpressed in HEK293 cells assessed as 2-AG hydrolysis at 1 uM by fluorescent glycerol assay | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
| 3. | ALA3373892 | B | Inhibition of human ABHD6 expressed in HEK293T cell membranes assessed as reduction in glycerol production using 2-arachidonoyl glycerol substrate | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 4. | ALA3405400 | B | Inhibition of human ABHD6 containing pCMV6-AC-hABHD6 transfected into HEK293 cells | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA3614814 | B | Inhibition of human ABHD6 expressed in HEK293 cells assessed as remaining enzyme activity by measuring reduction in glycerol production from 1-AG hydrolysis at 1 uM pre-incubated for 30 mins before 1-AG substrate addition and measured 90 mins post substrate addition by fluorescence method | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
| 6. | ALA3614931 | B | Inhibition of human ABHD6 expressed in HEK293 cells assessed as reduction in glycerol production from 1-AG hydrolysis pre-incubated for 30 mins before 1-AG substrate addition and measured 90 mins post substrate addition by fluorescence method | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 7. | ALA3614949 | B | Inhibition of human ABHD6 expressed in HEK293 cells at 1 uM pre-incubated for 10 mins before 2-AG substrate addition followed by rapid 40 fold compound dilution measured after 10 mins by HPLC method | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 8. | ALA3614950 | B | Inhibition of human ABHD6 expressed in HEK293 cells at 1 uM pre-incubated for 10 mins before 2-AG substrate addition followed by rapid 40 fold compound dilution measured after 30 mins by HPLC method | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA3614951 | B | Inhibition of human ABHD6 expressed in HEK293 cells at 1 uM pre-incubated for 10 mins before 2-AG substrate addition followed by rapid 40 fold compound dilution measured after 60 mins by HPLC method | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA3614952 | B | Inhibition of human ABHD6 expressed in HEK293 cells at 1 uM pre-incubated for 10 mins before 2-AG substrate addition followed by rapid 40 fold compound dilution measured after 90 mins by HPLC method | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA3614953 | B | Irreversible inhibition of human ABHD6 expressed in HEK293 cells at 1 uM pre-incubated for 10 mins before 2-AG substrate addition followed by rapid 40 fold compound dilution measured after 10 to 90 mins by HPLC method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA3614954 | B | Reversible inhibition of human ABHD6 expressed in HEK293 cells at 1 uM pre-incubated for 10 mins before 2-AG substrate addition followed by rapid 40 fold compound dilution measured after 10 to 90 mins by HPLC method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA3749737 | B | Inhibition of human ABHD6 expressed in HEK239 cells using 2-AG as substrate assessed as glycerol liberation at 10 uM preincubated for 30 mins followed by 2-AG addition measured for 90 mins by fluorescent glycerol assay relative to control | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
| 14. | ALA3749738 | B | Inhibition of human ABHD6 expressed in HEK239 cells using 2-AG as substrate assessed as glycerol liberation at 1 uM preincubated for 30 mins followed by 2-AG addition measured for 90 mins by fluorescent glycerol assay relative to control | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
| 15. | ALA3768671 | B | Inhibition of ABHD6 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 16. | ALA3879167 | B | Inhibition of human ABHD6 using 2-AG as natural substrate by fluorescence based assay | Homo sapiens | 27 | single protein format | Scientific Literature | ||
| 17. | ALA4032635 | B | Inhibition of human ABHD6 at 1 to 10 uM relative to control | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 18. | ALA4037470 | B | Inhibition of human ABHD6 expressed in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition measured after 5 mins by liquid scintillation spectroscopy analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4037977 | B | Inhibition of human ABHD6 at 10 uM | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 20. | ALA4150565 | B | Inhibition of rhodamine-tagged FP probe binding to ABHD6 in human SW620 cells at 0.1 to 10 uM pretreated for 2 hrs followed by rhodamine-tagged FP probe addition and measured after 30 mins by SDS-PAGE fluorescence analysis | Homo sapiens | 2 | cell-based format | Scientific Literature |
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