# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2209086 | B | Inhibition of ESD binding to FP-biotin in [12C][14N]-lysine, arginine and [13C6][15N2]-lysine, arginine labeled HEK293T cells at 20 uM after 1 hr by isotopic activity-based protein profiling-MudPIT assay | Homo sapiens | 1 | ALA2203175 | cell-based format | Scientific Literature | |
2. | ALA4623103 | B | Activation of human ESD expressed in HEK293T cells transfected with pEGFP-N1 at 0.1 uM after 24 hrs | Homo sapiens | 1 | ALA4622837 | cell-based format | Scientific Literature | |
3. | ALA4623104 | B | Activation of ESD in human L02 cells at 0.1 to 1 uM after 24 hrs | Homo sapiens | 1 | ALA4622837 | cell-based format | Scientific Literature | |
4. | ALA4623105 | B | Activation of human ESD expressed in HEK293T cells transfected with pEGFP-N1 assessed as protein redistribution in cytoplasm by fluorescence microscopic analysis | Homo sapiens | 1 | ALA4622837 | cell-based format | Scientific Literature | |
5. | ALA4623106 | B | Activation of human ESD expressed in HEK293T cells transfected with pEGFP-N1 assessed as compound co-localization with protein by fluorescence microscopic analysis | Homo sapiens | 1 | ALA4622837 | cell-based format | Scientific Literature | |
6. | ALA4623107 | B | Inhibition of IgG binding to ESD in human L02 cells by immuno precipitation assay | Homo sapiens | 1 | ALA4622837 | cell-based format | Scientific Literature | |
7. | ALA4623108 | B | Binding affinity to human ESD expressed in HEK293T cells assessed as association rate constant | Homo sapiens | 1 | ALA4622837 | cell-based format | Scientific Literature | |
8. | ALA4623109 | B | Binding affinity to human ESD expressed in HEK293T cells assessed as dissociation rate constant | Homo sapiens | 1 | ALA4622837 | cell-based format | Scientific Literature | |
9. | ALA4623110 | B | Binding affinity to human ESD expressed in HEK293T cells assessed as dissociation constant | Homo sapiens | 1 | ALA4622837 | cell-based format | Scientific Literature | |
10. | ALA4623111 | B | Activation of wild type human ESD expressed in HEK293T cells assessed as increase in protein mono ubiquitination at 0.1 to 1 uM incubated for 12 hrs by Western blot analysis | Homo sapiens | 1 | ALA4622837 | cell-based format | Scientific Literature | |
11. | ALA4623114 | B | Activation of human ESD expressed in HEK293T cells transfected with pEGFP-N1 assessed as induction of protein mono ubiquitination at 5 uM after 3 hrs by immunoblotting analysis | Homo sapiens | 1 | ALA4622837 | cell-based format | Scientific Literature | |
12. | ALA4623115 | B | Activation of human ESD expressed in HEK293T cells transfected with pEGFP-N1 assessed as induction of protein mono ubiquitination at 1 to 5 uM after 6 hrs by immunoblotting analysis | Homo sapiens | 1 | ALA4622837 | cell-based format | Scientific Literature | |
13. | ALA4623116 | B | Activation of human ESD expressed in HEK293T cells transfected with pEGFP-N1 assessed as increase in protein mono ubiquitination at 0.1 to 5 uM after 12 to 24 hrs by immunoblotting analysis | Homo sapiens | 1 | ALA4622837 | cell-based format | Scientific Literature | |
14. | ALA4623123 | B | Inhibition of IgG binding to human ESD expressed in HEK293T cells | Homo sapiens | 1 | ALA4622837 | cell-based format | Scientific Literature |