| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2208563 | B | Inhibition of aspartate aminotransferase using L-aspartate as substrate at 6 mM incubated for 1 hr prior to substrate addition measured after 30 mins by spectrophotometric analysis | 1 | single protein format | Scientific Literature | |||
| 2. | ALA3625341 | B | Inhibition of aspartate aminotransferase (unknown origin) at 4 mM using 5.55 mM L-aspartate as substrate | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 3. | ALA4232614 | B | Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by MDH1 enzyme-coupled fluorescence assay | Homo sapiens | 93 | single protein format | Scientific Literature | ||
| 4. | ALA4232615 | B | Inhibition of GOT1 (unknown origin) using aspartate and alpha-ketoglutarate as substrate after 20 mins by GLOX enzyme-coupled fluorescence assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 5. | ALA4885536 | B | Aspartate transaminase assay (GOT1) | Homo sapiens | 1 | single protein format | Donated Chemical Probes - SGC Frankfurt | ||
| 6. | ALA5105638 | B | Inhibition of GOT1 (unknown origin) | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 7. | ALA5105640 | B | Binding affinity to GOT1 (unknown origin) assessed as dissociation constant by microscale thermophoresis assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA5105641 | B | Inhibition of GOT1 (unknown origin) using aspartic acid and alpha-ketoglutaric acid as substrates assessed as reduction in absorbance of NADH incubated for 20 mins in presence of MDH1 and NADH by HTS assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 9. | ALA5105642 | B | Noncompetitive inhibition of GOT1 (unknown origin) using aspartic acid as substrate assessed as reduction in Vmax with constant Km at 0 to 40 uM by Michaelis-Menten equation based kinetic analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA5105643 | B | Noncompetitive inhibition of GOT1 (unknown origin) using alpha-Ketoglutaric acid as substrate assessed as reduction in Vmax with constant Km at 0 to 40 uM by Michaelis-Menten equation based kinetic analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA5105644 | B | Noncompetitive inhibition of GOT1 (unknown origin) using aspartic acid as substrate assessed as inhibition constant by Michaelis-Menten equation based kinetic analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 12. | ALA5105645 | B | Noncompetitive inhibition of GOT1 (unknown origin) using alpha-Ketoglutaric acid as substrate assessed as inhibition constant by Michaelis-Menten equation based kinetic analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 13. | ALA5105646 | B | Noncompetitive inhibition of GOT1 (unknown origin) using aspartic acid and alpha-ketoglutaric acid as substrate incubated in presence of pyridoxal 5'-phosphate | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 14. | ALA5105647 | B | Reversible inhibition of GOT1 (unknown origin) at 10 fold IC50 preincubated for 30 mins followed by dilution to 0.5 fold IC50 and measured after 20 mins by dilution assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 15. | ALA5105650 | B | Inhibition of human recombinant GOT1 expressed in Escherichia coli BL21 star DE3 cells using aspartic acid and alpha-ketoglutaric acid as substrates incubated in presence of MDH1 and NADH | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA5105651 | B | Inhibition of human recombinant GOT1 using aspartic acid and alpha-ketoglutaric acid as substrates incubated in presence of MDH1 and NADH | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 17. | ALA5105652 | B | Inhibition of C-terminal His6-tagged human recombinant GOT1 expressed in Escherichia coli BL21 (DE3) cells using aspartic acid and alpha-ketoglutaric acid as substrates incubated in presence of MDH1 and NADH | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 18. | ALA5217610 | B | Inhibition of GOT1 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature |
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