| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2217296 | B | Inhibition of PI3Kdelta-mediated AKT phosphorylation in mouse Raw 264.7 cells by immunoassay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA3868301 | B | Inhibition of PI3K-delta in mouse splenocytes assessed as inhibition anti-IgM induced CD86 expression | Mus musculus | 16 | cell-based format | Scientific Literature | ||
| 3. | ALA3880144 | B | Inhibition of PI3Kdelta in LPS or anti-CD40/IL4-stimulated mouse B cells assessed as decrease in IgG response in presence of mTOR inhibitor rapamycin relative to vehicle-treated control | Mus musculus | 1 | cell-based format | Patent Bioactivity Data | ||
| 4. | ALA3880145 | B | Inhibition of PI3Kdelta in LPS or anti-CD40/IL4-stimulated mouse B cells assessed as decrease in IgE response in presence of mTOR inhibitor rapamycin | Mus musculus | 1 | cell-based format | Patent Bioactivity Data | ||
| 5. | ALA3996858 | B | Inhibition of PI3Kdelta in mouse spleen assessed suppression of CD86 | Mus musculus | 1 | single protein format | Scientific Literature | ||
| 6. | ALA4016624 | B | Inhibition of PI3Kdelta in mouse whole blood | Mus musculus | 1 | single protein format | Scientific Literature | ||
| 7. | ALA4134215 | B | Inhibition of PI3Kdelta in Balb/c mouse splenocytes assessed as reduction in anti-IgM stimulated CD86 expression pretreated for 1 hr followed by anti-IgM stimulation after 24 hrs by flow cytometric analysis | Mus musculus | 12 | cell-based format | Scientific Literature | ||
| 8. | ALA4134217 | B | Inhibition of PI3Kdelta in mouse B cells assessed as reduction in anti-IgM-induced cell proliferation measured last 16 hrs of 88 hrs incubation by [3H]thymidine incorporation assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4134228 | B | Inhibition of PI3Kdelta in mouse spleen cells assessed as reduction in cell proliferation by measuring [3H]thymidine incorporation by beta counting based mixed lymphocyte reaction assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4134229 | B | Inhibition of PI3Kdelta in anti-CD3/CD28 stimulated mouse CD4-positive T cells assessed as reduction in T cell differentiation to Th2 cells by measuring IL-13 level after 72 hrs by ELISA | Mus musculus | 1 | assay format | Scientific Literature | ||
| 11. | ALA4134230 | B | Inhibition of PI3Kdelta in anti-CD3/CD28 stimulated mouse CD4-positive T cells assessed as reduction in T cell differentiation to Th17 cells by measuring IL-17A level after 72 hrs by ELISA | Mus musculus | 1 | assay format | Scientific Literature | ||
| 12. | ALA4158815 | B | Inhibition of mouse ABD-truncated p110delta catalytic subunit (unknown origin) expressed in Sf9 cells using diC8-PIP2 substrate incubated for 1 hr by fluorescence polarization assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4232710 | B | Inhibition of PI3Kdelta in Balb/c mouse splenocytes-derived B cells assessed as reduction in anti-IgM antibody-stimulated B cell proliferation after 2 days alamar blue assay | Mus musculus | 12 | cell-based format | Scientific Literature | ||
| 14. | ALA4428713 | B | Inhibition of PI3Kdelta in BALB/c mouse B cells assessed as reduction in Anti-IgM induced AKT Ser473 phosphorylation pre-incubated for 45 mins before Anti-IgM stimulation | Mus musculus | 17 | cell-based format | Scientific Literature | ||
| 15. | ALA4430049 | B | Inhibition of PI3Kdelta in Balb/c mouse B cells assessed as reduction in anti-IgM induced CD86 expression preincubated for 1 hr followed by anti-IgM stimulation for 24 hrs by flow cytometry | Mus musculus | 12 | cell-based format | Scientific Literature | ||
| 16. | ALA4430059 | B | Inhibition of PI3Kdelta in Balb/c mouse in rat B cells assessed as reduction in anti-IgM induced proliferation measured over last 16 hrs of 88 hrs by [3H]-Thymidine incorporation assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4716074 | B | Inhibition of PI3Kdelta in Balb/c mouse B cells assessed as inhibition of antiIgM-induced Akt phosphorylation at ser 473 residue preincubated for 45 mins followed by antiIgM stimulation and measured after 15 mins by immunostaining based flow cytometry analysis | Mus musculus | 4 | cell-based format | Scientific Literature | ||
| 18. | ALA4835474 | B | Inhibition of mouse PI3Kdelta | Mus musculus | 1 | single protein format | Scientific Literature | ||
| 19. | ALA4835506 | B | Inhibition of PI3Kdelta in Foxp3-GFP C57BL/6 mouse assessed as reduction in Treg population administered upto 7 days | Mus musculus | 1 | single protein format | Scientific Literature | ||
| 20. | ALA4835507 | B | Inhibition of PI3Kdelta in Foxp3-GFP C57BL/6 mouse assessed as reduction in Treg population at 30 to 100 mg/kg administered upto 7 days | Mus musculus | 1 | organism-based format | Scientific Literature |
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