| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5253221 | F | Induction of DNA interstrand cross-linking in hydrogen peroxide induced human NCI/ADR-RES cells assessed as decrease in comet tail density at 10 uM incubated for 90 mins by comet assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA5253258 | F | Induction of DNA interstrand cross-linking in hydrogen peroxide induced human NCI/ADR-RES cells assessed as decrease in comet tail density at 100 uM incubated for 90 mins by comet assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 3. | ALA5253259 | F | Synergistic induction of DNA interstrand cross-linking in hydrogen peroxide induced human NCI/ADR-RES cells assessed as decrease in comet tail density at 100 uM incubated for 90 mins in presence of formaldehyde by comet assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA5253260 | F | Synergistic induction of DNA interstrand cross-linking in hydrogen peroxide induced human NCI/ADR-RES cells assessed as decrease in comet tail density at 100 uM incubated for 90 mins in presence of doxorubicin by comet assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA5253261 | F | Synergistic induction of DNA interstrand cross-linking in hydrogen peroxide induced human NCI/ADR-RES cells assessed as decrease in comet tail density at 100 uM incubated for 90 mins in presence of epirubicin by comet assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA5253262 | F | Synergistic induction of DNA interstrand cross-linking in hydrogen peroxide induced human NCI/ADR-RES cells assessed as decrease in comet tail density at 5 uM incubated for 90 mins in presence of formaldehyde by comet assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA5253263 | F | Synergistic induction of DNA interstrand cross-linking in hydrogen peroxide induced human NCI/ADR-RES cells assessed as decrease in comet tail density at 100 uM incubated for 90 mins in presence of 5 uM of epirubicin by comet assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA5253264 | F | Synergistic induction of DNA interstrand cross-linking in hydrogen peroxide induced human NCI/ADR-RES cells assessed as decrease in comet tail density at 100 uM incubated for 90 mins in presence of 5 uM of doxorubicin by comet assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA3614802 | B | Stabilization of human telomere promoter G-quadruplex DNA (unknown origin) | Homo sapiens | 2 | nucleic acid format | Scientific Literature | ||
| 10. | ALA3632372 | B | Binding affinity to AATTCAATT-AATTGAATT DNA fragment (unknown origin) by DNaseI footprinting analysis | Homo sapiens | 2 | nucleic acid format | Scientific Literature | ||
| 11. | ALA3632373 | B | Binding affinity to AATTGCAATT-AATTGCAATT DNA fragment (unknown origin) by DNaseI footprinting analysis | Homo sapiens | 2 | nucleic acid format | Scientific Literature | ||
| 12. | ALA3632374 | B | Binding affinity to A4CT4-A4GT4 DNA fragment (unknown origin) by DNaseI footprinting analysis | Homo sapiens | 2 | nucleic acid format | Scientific Literature | ||
| 13. | ALA3631677 | B | Binding affinity to human truncated telomeric DNA1 assessed as melting temperature at 20 uM by UV melting curve analysis (Rvb = 58.9 +/- 0.3 degC) | Homo sapiens | 4 | nucleic acid format | Scientific Literature | ||
| 14. | ALA4142154 | B | Binding affinity to single-stranded DNA (unknown origin) assessed as DNA intercalation by measuring increase in relative viscosity of DNA-compound complex by viscometry | Not specified | 2 | nucleic acid format | Scientific Literature | ||
| 15. | ALA4142155 | B | Binding affinity to single-stranded DNA (unknown origin) after 10 mins by UV-visible spectrometric method | Not specified | 6 | nucleic acid format | Scientific Literature | ||
| 16. | ALA4142160 | B | Binding affinity to single-stranded DNA (unknown origin) assessed as red shift up to 72 uM after 10 mins by UV-visible spectrometric method | Not specified | 6 | nucleic acid format | Scientific Literature | ||
| 17. | ALA4232341 | B | Binding affinity to human estrogen receptor DNA assessed as estrogen receptor PCR product formation | Homo sapiens | 1 | nucleic acid format | Scientific Literature | ||
| 18. | ALA4232342 | B | Binding affinity to Ha-ras DNA (unknown origin) assessed as Ha-ras PCR product formation | Not specified | 1 | nucleic acid format | Scientific Literature | ||
| 19. | ALA4252830 | B | Binding affinity to circulating tumor DNA (unknown origin) at 100 uM preincubated for 30 mins in presence of Hoechst 33342 followed by compound addition measured after 30 mins by fluorescence assay | Not specified | 1 | nucleic acid format | Scientific Literature | ||
| 20. | ALA4264759 | B | Binding affinity to ER04 single stranded DNA (unknown origin) at DNA to compound ratio of 1:2.5 to 1:10 after 20 mins by ESI-MS analysis | Not specified | 1 | nucleic acid format | Scientific Literature |
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