# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4381108 | B | Binding affinity to total RNA in human PANC1 cells assessed as increase in amount of KRAS mRNA in recovered RNA from biotin-streptavidin pulled down at 0.2 to 0.6 uM at pH 7.4 and 4 degree C using biotinylated compound by qRT-PCR analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
2. | ALA4381109 | B | Binding affinity to total RNA in human PANC1 cells assessed as increase in amount of HPRT mRNA in recovered RNA from biotin-streptavidin pulled down at 0.2 to 0.6 uM at pH 7.4 and 4 degree C using biotinylated compound by qRT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA4381110 | B | Binding affinity to total RNA in human PANC1 cells assessed as increase in amount of beta2-microglobulin mRNA in recovered RNA from biotin-streptavidin pulled down at 0.2 to 0.6 uM at pH 7.4 and 4 degree C using biotinylated compound by qRT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
4. | ALA4381111 | B | Binding affinity to total RNA in human PANC1 cells assessed as increase in amount of NRAS mRNA in recovered RNA from biotin-streptavidin pulled down at 0.2 to 0.6 uM at pH 7.4 and 4 degree C using biotinylated compound by qRT-PCR analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
5. | ALA4430916 | B | Binding affinity to RNA (unknown origin) assessed as inhibition of fluorescent dsRNA probe binding to DNA at 200 uM at 200 uM pre-incubated for 5 mins before dsRNA addition and measured after 5 mins by ethidium bromide displacement based EMSA method relative to control | Not specified | 11 | nucleic acid format | Scientific Literature | ||
6. | ALA4710751 | B | Binding affinity to major groove of ds-RNA (unknown origin) assessed as positive ICD band by CD spectroscopy | Not specified | 2 | nucleic acid format | Scientific Literature |