| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2317834 | B | Inhibition of human recombinant Dicer-mediated pre-miR-29a without bulge loop processing assessed as reduction of mature miR-29a formation by Northern blot analysis (Rvb = 51%) | Homo sapiens | 1 | ALA2311396 | single protein format | Scientific Literature | |
| 2. | ALA2317835 | B | Inhibition of human recombinant Dicer-mediated pre-miR-29a without internal loop processing assessed as reduction of mature miR-29a formation by Northern blot analysis (Rvb = 30%) | Homo sapiens | 1 | ALA2311396 | single protein format | Scientific Literature | |
| 3. | ALA2317836 | B | Inhibition of human recombinant Dicer-mediated pre-miR-29a processing assessed as reduction of mature miR-29a formation by Northern blot analysis (Rvb = 41%) | Homo sapiens | 1 | ALA2311396 | single protein format | Scientific Literature | |
| 4. | ALA2317837 | B | Inhibition of human recombinant Dicer-mediated long dsRNA digestion assessed as 21- to 23-mer short RNA formation at 200 uM after 3 hrs by denaturing-PAGE analysis | Homo sapiens | 6 | ALA2311396 | single protein format | Scientific Literature | |
| 5. | ALA2317838 | B | Inhibition of human recombinant Dicer-mediated pre-miR-29a processing assessed as reduction of mature miR-29a formation at 200 uM after 3 hrs by Northern blot analysis | Homo sapiens | 6 | ALA2311396 | single protein format | Scientific Literature | |
| 6. | ALA3855684 | B | Effect on Dicer (unknown origin) assessed as effect on 5'-gamma32P-ATP labeled pre-miRNA processing at 5 uM after 15 mins by gel electrophoresis assay | Homo sapiens | 1 | ALA3853344 | single protein format | Scientific Literature | |
| 7. | ALA4150512 | B | Binding affinity to dicer (unknown origin) assessed as inhibition of dicer-meditated pre-let-7d microRNA maturation at 100 uM by electrophoretic mobility shift assay | Homo sapiens | 2 | ALA4145627 | single protein format | Scientific Literature | |
| 8. | ALA4329772 | B | Inhibition of recombinant FLAG-tagged human dicer expressed in HEK293 cells assessed as reduction in pre-let-7g microRNA maturation at 5 to 10 uM after 40 mins by SYBR green2 dye based fluorescence assay | Homo sapiens | 1 | ALA4325922 | cell-based format | Scientific Literature |
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