| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3822105 | B | Binding affinity to E-cadherin in human OAW42 cells assessed as effect on PI3K/Akt signalling activation by measuring phosphorylation of Akt at Ser-473 residue at 1 to 2 mM by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA3822106 | B | Inhibition of E-cadherin-Fc chimeric protein binding to E-cadherin in human OAW42 cells at 2 mM preincubated for 1 hr followed by E-cadherin-Fc addition measured after 2 hrs by ELISA relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 3. | ALA4824237 | B | Disruption of full length beta-catenin/E-cadherin interaction in human HCT116 cells incubated for 24 hrs by co-immunoprecipitation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA5110745 | B | Binding affinity to human E-cadherin in human MKN-7 cell membrane protein fraction measured after 2 hrs by Western blotting based pull-down assay | Homo sapiens | 1 | cell membrane format | Scientific Literature |
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