# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA985174 | B | Inhibition of rat Nav1.3 channel expressed in Xenopus oocytes by whole cell voltage clamp technique | Rattus norvegicus | 1 | ALA1156508 | cell-based format | Scientific Literature | |
2. | ALA1918329 | B | Inhibition of rat Nav1.3 expressed in Xenopus oocytes assessed as blockage of voltage-activated sodium current at holding potential of -100 mV by two-electrode voltage-clamp electrophysiology | Rattus norvegicus | 2 | ALA1914383 | cell-based format | Scientific Literature | |
3. | ALA1918335 | B | Inhibition of rat Nav1.3 expressed in Xenopus oocytes assessed as blockage of voltage-activated sodium current at 100 uM and at holding potential of -100 mV by two-electrode voltage-clamp electrophysiology | Rattus norvegicus | 1 | ALA1914383 | cell-based format | Scientific Literature | |
4. | ALA1918438 | B | Inhibition of rat Nav1.3 expressed in Xenopus oocytes assessed as blockage of voltage-activated sodium current at 300 uM and at holding potential of -100 mV by two-electrode voltage-clamp electrophysiology | Rattus norvegicus | 1 | ALA1914383 | cell-based format | Scientific Literature | |
5. | ALA2328108 | B | Inhibition of rat voltage-gated Na channel 1.3 in dorsal root ganglion neurons by patch clamp technique | Rattus norvegicus | 1 | ALA2321869 | tissue-based format | Scientific Literature | |
6. | ALA2328118 | B | Binding affinity to rat inactivated voltage-gated Na channel 1.3 expressed in human HEK293 cells by patch-clamp technique | Rattus norvegicus | 1 | ALA2321869 | cell-based format | Scientific Literature | |
7. | ALA3592066 | B | Inhibition of rat Nav1.3 expressed in HEK293 cells assessed as transition of channels to slow-inactivated state at 10 uM measured at -50 mV by whole cell patch-clamp electrophysiology | Rattus norvegicus | 1 | ALA3588826 | cell-based format | Scientific Literature | |
8. | ALA3592070 | B | Inhibition of rat Nav1.3 expressed in HEK293 cells assessed as half-maximal voltage for steady state activation at 10 uM by whole cell patch-clamp electrophysiology (Rvb = -29.62 +/-3.59 mV) | Rattus norvegicus | 1 | ALA3588826 | cell-based format | Scientific Literature | |
9. | ALA3592074 | B | Inhibition of rat Nav1.3 expressed in HEK293 cells assessed as half-maximal voltage for steady state fast-inactivation at 10 uM by whole cell patch-clamp electrophysiology (Rvb = -65.44 +/-5.62 mV) | Rattus norvegicus | 1 | ALA3588826 | cell-based format | Scientific Literature | |
10. | ALA3592078 | B | Frequency-dependent inhibition of rat Nav1.3 expressed in HEK293 cells assessed as current amplitude at 10 uM by whole cell patch-clamp electrophysiology | Rattus norvegicus | 1 | ALA3588826 | cell-based format | Scientific Literature | |
11. | ALA3618947 | B | Inhibition of rat NaV1.3 channel | Rattus norvegicus | 1 | ALA3616397 | single protein format | Scientific Literature | |
12. | ALA3880174 | B | Inhibition of rat NaV1.3 | Rattus norvegicus | 1 | ALA3879903 | single protein format | Patent Bioactivity Data | |
13. | ALA4257699 | B | Inhibition of rat NaV1.3 by electrophysiological method | Rattus norvegicus | 1 | ALA4257443 | single protein format | Scientific Literature | |
14. | ALA4257756 | B | Inhibition of rat NaV1.3 expressed in HEK293 cells at -80V holding potential by whole-cell patch-Clamp method | Rattus norvegicus | 1 | ALA4257443 | cell-based format | Scientific Literature | |
15. | ALA5037532 | B | Modulator activity at rat Nav1.3 expressed in Xenopus laevis oocytes assessed as elicitation in sodium current measured after 1 to 4 days by two-electrode voltage clamp assay | Rattus norvegicus | 7 | ALA5036335 | cell-based format | Scientific Literature | |
16. | ALA5125243 | B | Effect on rat Nav1.3 expressed in Xenopus laevis oocytes at 10 uM at holding potential of -90 mV by patch clamp electrophysiology | Rattus norvegicus | 1 | ALA5120921 | cell-based format | Scientific Literature |