| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2327220 | B | Inhibition of Mycobacterium tuberculosis CysK1 using O-acetyl-L-serine as substrate assessed as L-cycteine formation after 5 mins by spectrophotometric analysis | Mycobacterium tuberculosis | 5 | ALA2321837 | single protein format | Scientific Literature | |
| 2. | ALA2327376 | B | Inhibition of Mycobacterium tuberculosis CysK1 using O-acetyl-L-serine as substrate assessed as L-cycteine formation at 100 uM after 5 mins by spectrophotometric analysis relative to control | Mycobacterium tuberculosis | 32 | ALA2321837 | single protein format | Scientific Literature | |
| 3. | ALA2327377 | B | Competitive inhibition of Mycobacterium tuberculosis CysK1 | Mycobacterium tuberculosis | 1 | ALA2321837 | single protein format | Scientific Literature | |
| 4. | ALA2423412 | B | Ratio of BAS02513208 IC50 to compound IC50 for Mycobacterium tuberculosis N-terminal His-6-tagged recombinant CysK1 | Mycobacterium tuberculosis | 1 | ALA2417551 | single protein format | Scientific Literature | |
| 5. | ALA2423414 | B | Ratio of DFSI tetrapeptide IC50 to compound IC50 for Mycobacterium tuberculosis N-terminal His-6-tagged recombinant CysK1 | Mycobacterium tuberculosis | 1 | ALA2417551 | single protein format | Scientific Literature | |
| 6. | ALA2423608 | B | Inhibition of Mycobacterium tuberculosis N-terminal His-6-tagged recombinant CysK1 expressed in Escherichia coli BL21 (DE3) after 20 mins by spectrophotometric analysis | Mycobacterium tuberculosis | 79 | ALA2417551 | assay format | Scientific Literature | |
| 7. | ALA2423609 | B | Inhibition of Mycobacterium tuberculosis N-terminal His-6-tagged recombinant CysK1 expressed in Escherichia coli BL21 (DE3) at 500 nM after 20 mins by spectrophotometric analysis | Mycobacterium tuberculosis | 98 | ALA2417551 | assay format | Scientific Literature | |
| 8. | ALA2423610 | B | Inhibition of Mycobacterium tuberculosis CysK1 | Mycobacterium tuberculosis | 2 | ALA2417551 | single protein format | Scientific Literature | |
| 9. | ALA2423611 | B | Competitive inhibition of Mycobacterium tuberculosis CysK1 | Mycobacterium tuberculosis | 1 | ALA2417551 | single protein format | Scientific Literature | |
| 10. | ALA5262985 | B | Inhibition of hexahistidine-tagged recombinant Mycobacterium tuberculosis CysK1 expressed in Escherichia coli BL21(DE3) assessed as dissociation constant using PLP as substrate incubated for 5 mins by fluorescence analysis | Mycobacterium tuberculosis | 5 | ALA5260815 | assay format | Scientific Literature | |
| 11. | ALA5262989 | B | Inhibition of hexahistidine-tagged recombinant Mycobacterium tuberculosis CysK1 expressed in Escherichia coli BL21(DE3) assessed as amount of cysteine produced using O-acetyl-L-serine as substrate incubated for 12 mins by acid-ninhydrin based spectrophotometric assay | Mycobacterium tuberculosis | 12 | ALA5260815 | assay format | Scientific Literature |
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