| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2327431 | B | Inhibition of human TREK-1 expressed in HEK293 cells by patch-clamp technique | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA2327432 | B | Inhibition of TREK-1 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 3. | ALA3132222 | B | Reversible activation of TREK1 channel (unknown origin) expressed in Xenopus oocytes assessed as channel current at 20 uM incubated for 15 mins measured post compound wash-out by two-microelectrode voltage-clamp technique | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
| 4. | ALA3132223 | B | Activation of TREK1 channel (unknown origin) expressed in Xenopus oocytes assessed as ratio of current in presence of compound to current in absence of compound at 20 uM incubated for 15 mins by two-microelectrode voltage-clamp technique | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
| 5. | ALA3819802 | B | Activation of TREK1 (unknown origin) expressed in COS7 cells assessed as increase in whole cell currents at 100 uM at +50 mV relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA3819803 | B | Activation of TREK1 (unknown origin) expressed in COS7 cells assessed as increase in whole cell currents at +50 mV relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA3819804 | B | Activation of human TREK1 expressed in CHO cells assessed as increase in channel currents at 10 uM relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA3819805 | B | Activation of TREK1 (unknown origin) expressed in COS7 cells assessed as increase in whole cell currents at 10 uM relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA3819806 | B | Activation of TREK1 (unknown origin) expressed in Xenopus oocytes assessed as increase in channel currents at 20 uM relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA3819807 | B | Activation of TREK1 (unknown origin) expressed in bAZF cells assessed as increase in current density at 10 uM relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA3819808 | B | Activation of TREK1 (unknown origin) expressed in bAZF cells assessed as increase in current density at 20 uM relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA3819809 | B | Activation of TREK1 (unknown origin) expressed in HEK293 cells assessed as increase in current density at 100 uM relative to control | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 13. | ALA3819810 | B | Activation of human TREK1 expressed in CHO cells assessed as increase in channel currents at 10 uM at +50 mV relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 14. | ALA3819812 | B | Activation of TREK1 (unknown origin) expressed in bAZF cells assessed as increase in current density at 40 uM relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA3819813 | B | Activation of human TREK1 expressed in CHO cells assessed as increase in channel currents at 100 nM at +50 mV relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA3819814 | B | Activation of human TREK1 expressed in CHO cells assessed as increase in channel currents at +50 mV relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA3819815 | B | Activation of TREK1 (unknown origin) expressed in Xenopus oocytes assessed as increase in channel currents at 100 uM relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 18. | ALA3819816 | B | Activation of TREK1 (unknown origin) expressed in Xenopus oocytes assessed as increase in channel currents | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 19. | ALA3819817 | B | Activation of TREK1 (unknown origin) expressed in HEK293 cells assessed as increase in current density relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA3819818 | B | Activation of TREK1 (unknown origin) expressed in HEK293 cells assessed as increase in channel currents at 1 uM relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature |
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