| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3117009 | B | Inhibition of Tyk2 in mouse BA/F3 cells expressing TEL-Tyk2 assessed as inhibition of STAT5 phosphorylation by Western blotting analysis | Mus musculus | 1 | ALA3112447 | cell-based format | Scientific Literature | |
| 2. | ALA3602081 | B | Inhibition of TYK2 in mouse BMDM assessed as inhibition of IL-10-induced STAT3 phosphorylation at 5 uM preincubated for 3 hrs followed by IL-4 induction measured after 30 mins by immunoblotting | Mus musculus | 3 | ALA3600288 | single protein format | Scientific Literature | |
| 3. | ALA4377382 | B | Inhibition of TYK2 in mouse whole blood assessed as decrease in IFNalpha-induced STAT1 phosphorylation preincubated for 1 hr followed by stimulation with IFN-alpha for 15 mins by fluorescence analysis | Mus musculus | 15 | ALA4376812 | tissue-based format | Scientific Literature | |
| 4. | ALA4414800 | B | Inhibition of TYK2 JH2 domain in mouse whole blood assessed as inhibition of IFNalpha-induced STAT1 phosphorylation preincubated for 1 hr followed by IFNalpha stimulation and measured after 15 mins by fluorescence assay | Mus musculus | 8 | ALA4414548 | tissue-based format | Scientific Literature | |
| 5. | ALA4775564 | B | Inhibition of TYK2 in mouse whole blood assessed as decrease in IFNalpha-induced STAT5 phosphorylation | Mus musculus | 1 | ALA4765480 | tissue-based format | Scientific Literature |
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