# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3706360 | Binding | Receptor Binding Assay: Human monocytic cell line THP-1 cells were obtained from American Type Culture Collection (Manassas, Va., USA). The THP-1 cells were grown in RPMI-1640 (RPMI: Roswell Park Memorial Institute Medium-cell culture growth media) supplemented with 10% fetal bovine serum in a humidified 5% CO2 atmosphere at 37° C. The cell density was maintained between 0.5×106 cells/mL. | 154 | ALA3639313 | cell-based format | BindingDB Database | ||
2. | ALA2328025 | Binding | Antagonist activity at CCR11 (unknown origin) assessed as inhibition of chemotaxis at 10 uM | Homo sapiens | 1 | ALA2321873 | single protein format | Scientific Literature | |
3. | ALA2328618 | Functional | Antagonist activity at CCR11 (unknown origin) assessed as inhibition of calcium flux at 10 uM | Homo sapiens | 1 | ALA2321873 | single protein format | Scientific Literature | |
4. | ALA2328639 | Binding | Binding affinity to CCR11 (unknown origin) at 10 uM by radioligand displacement assay | Homo sapiens | 1 | ALA2321873 | single protein format | Scientific Literature | |
5. | ALA4883338 | Binding | PRESTO-Tango GPCRome screening (CCRL2) | 1 | ALA4507309 | single protein format | Donated Chemical Probes - SGC Frankfurt |