| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2330199 | B | Inhibition of SUV420H1 (unknown origin) using histone H4 (1 to 24)K20Me1 as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenosylmethionine | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 2. | ALA3111731 | B | Inhibition of SUV420H1 (unknown origin)-mediated incorporation of methyl group from [3H]-SAM into peptide substrate up to 50 uM by scintillation proximity assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 3. | ALA3378210 | B | Inhibition of SUV420H1 (unknown origin) assessed as incorporation of tritium-labeled methyl group to lysine or arginine residues of peptide substrate by radioactive assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 4. | ALA3592398 | B | Inhibition of SUV420H1 (unknown origin) assessed as incorporation of tritium labeled methyl group from [3H]-SAM to substrate at 1 uM after 1 hr by scintillation proximity assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 5. | ALA3784102 | B | Inhibition of human SUV420H1 at 10 and 50 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 6. | ALA3821906 | B | Inhibition of SUV420H1 (unknown origin) at 1 to 50 uM by scintillation proximity assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA3859075 | B | Inhibition of SUV420H1 (unknown origin) at 50 uM using biotin-labeled peptide as substrate and [3H]-SAM measured after 1 hr by scintillation proximity assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA4005614 | B | Inhibition of SUV420H1 (unknown origin) at 10 uM using biotin-labeled peptide as substrate and [3H]-SAM measured after 1 hr by scintillation proximity assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA4005643 | B | Inhibition of SUV420H1 (unknown origin) at 1 uM using biotin-labeled peptide as substrate and [3H]-SAM measured after 1 hr by scintillation proximity assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA4346628 | B | Inhibition of SUV420H1 (unknown origin) assessed as reduction in incorporation of [3H]-labeled methyl group into biotinylated substrate using [3H-SAM] at 10 uM incubated for 1 hr by scintillation proximity assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA4376157 | B | Inhibition of SUV420H1 (unknown origin) at 1 uM using biotin-labeled peptide as substrate and [3H]-SAM measured after 1 hr by scintillation proximity assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 12. | ALA4376160 | B | Inhibition of SUV420H1 in human MCF7 cells assessed as decrease in H4K20me3 level up to 50 uM measured after 2 days by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4377313 | B | Inhibition of human SUV420H1 up to 50 uM using Biot-H4K20me1 as substrate and in presence of [3H]-SAM incubated for 1 hr by scintillation proximity assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 14. | ALA4480250 | B | Inhibition of SUV420H1 (unknown origin) using biotin-labeled histone substrate assessed as residual activity at 50 uM in presence of [3H-Me]SAM by scintillation proximity assay relative to control | Homo sapiens | 24 | single protein format | Scientific Literature | ||
| 15. | ALA4731567 | B | Inhibition of recombinant human N-terminal GST-tagged SUV420H1 (2 to 393 residues ) expressed in baculovirus infected Sf9 cells using core histone as substrate at 10 uM by radiometric HotSpot assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4833664 | B | Inhibition of SUV4-20H1 (unknown origin) at 10 uM using SAM as substrate measured up to 960 mins by AlphaScreen microplate reader assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 17. | ALA5030786 | B | Inhibition of SUV420H1 (unknown origin) at 1 to 10 uM | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 18. | ALA5119858 | B | Inhibition of human recombinant N-terminal GST-tagged SUV420H1-tv2 (2 to 393 residues) expressed in baculovirus infected insect cell at 10 uM using histone as substrate by scintillation/filter plate assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 19. | ALA5119896 | B | Inhibition of human recombinant N-terminal GST-tagged SUV420H1-tv2 (2 to 393 residues) expressed in baculovirus infected insect cell at 50 uM using histone as substrate by scintillation/filter plate assay relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 20. | ALA5210094 | B | Affinity Phenotypic Cellular interaction (Western Blot (decrease in di-methylation of H4K20me in U20S cells)) EUB0000193b SUV420H1 | Homo sapiens | 1 | cell-based format | Literature data from EUbOPEN Chemogenomic Library |
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