| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2330201 | B | Inhibition of SETDB1 (unknown origin) using histone H3 (1 to 25) as substrate after 0.25 hrs by scintillation proximity assay in presence of [3H]-S-adenosylmethionine | Homo sapiens | 1 | ALA2321656 | single protein format | Scientific Literature | |
| 2. | ALA3111903 | B | Inhibition of SETDB1 (unknown origin)-mediated incorporation of methyl group from [3H]-SAM into peptide substrate up to 50 uM by scintillation proximity assay | Homo sapiens | 1 | ALA3108684 | single protein format | Scientific Literature | |
| 3. | ALA3378203 | B | Inhibition of SETDB1 (unknown origin) assessed as incorporation of tritium-labeled methyl group to lysine or arginine residues of peptide substrate by radioactive assay | Homo sapiens | 1 | ALA3351294 | single protein format | Scientific Literature | |
| 4. | ALA3399136 | B | Inhibition of SETDB1 (unknown origin) by HMT assay | Homo sapiens | 2 | ALA3396964 | single protein format | Scientific Literature | |
| 5. | ALA3399144 | B | Inhibition of SETDB1 (unknown origin) at 10 uM by HMT assay | Homo sapiens | 1 | ALA3396964 | single protein format | Scientific Literature | |
| 6. | ALA3592289 | B | Inhibition of SETDB1 (unknown origin) assessed as incorporation of tritium labeled methyl group from [3H]-SAM to substrate at 1 uM after 1 hr by scintillation proximity assay relative to control | Homo sapiens | 1 | ALA3588844 | single protein format | Scientific Literature | |
| 7. | ALA3784097 | B | Inhibition of human SETDB1 at 10 and 50 uM | Homo sapiens | 1 | ALA3779843 | single protein format | Scientific Literature | |
| 8. | ALA3803384 | B | Inhibition of SETDB1 (unknown origin) at 10 uM relative to control | Homo sapiens | 2 | ALA3797202 | single protein format | Scientific Literature | |
| 9. | ALA3821564 | B | Inhibition of SETDB1 (unknown origin) at 1 to 50 uM by scintillation proximity assay | Homo sapiens | 1 | ALA3817823 | single protein format | Scientific Literature | |
| 10. | ALA3859070 | B | Inhibition of SETDB1 (unknown origin) at 50 uM using biotin-labeled peptide as substrate and [3H]-SAM measured after 1 hr by scintillation proximity assay | Homo sapiens | 1 | ALA3856251 | single protein format | Scientific Literature | |
| 11. | ALA4005611 | B | Inhibition of SETDB1 (unknown origin) at 10 uM using biotin-labeled peptide as substrate and [3H]-SAM measured after 1 hr by scintillation proximity assay | Homo sapiens | 1 | ALA4004823 | single protein format | Scientific Literature | |
| 12. | ALA4005640 | B | Inhibition of SETDB1 (unknown origin) at 1 uM using biotin-labeled peptide as substrate and [3H]-SAM measured after 1 hr by scintillation proximity assay | Homo sapiens | 1 | ALA4004823 | single protein format | Scientific Literature | |
| 13. | ALA4346622 | B | Inhibition of SETDB1 (unknown origin) assessed as reduction in incorporation of [3H]-labeled methyl group into biotinylated substrate using [3H-SAM] at 10 uM incubated for 1 hr by scintillation proximity assay | Homo sapiens | 1 | ALA4342528 | single protein format | Scientific Literature | |
| 14. | ALA4377301 | B | Inhibition of human SETDB1 up to 50 uM using Biot-H3 (1-25) as substrate and in presence of [3H]-SAM incubated for 1 hr by scintillation proximity assay | Homo sapiens | 1 | ALA4376809 | single protein format | Scientific Literature | |
| 15. | ALA4379085 | B | Binding affinity to SETDB1 (unknown origin) at protein to compound concentration ratio of 1:10 by differential scanning fluorimetry | Homo sapiens | 1 | ALA4376834 | single protein format | Scientific Literature | |
| 16. | ALA4387483 | B | Binding affinity to N-terminal His6-tagged human SETDB1 Tudor domain (197 to 403 residues) expressed in Escherichia coli BL21(DE3)-pRARE2 cells assessed as induction of HSQC shift at 10 mM by 1H-15 N HSQC-TROSY NMR spectroscopy | Homo sapiens | 1 | ALA4385651 | cell-based format | Scientific Literature | |
| 17. | ALA4387484 | B | Binding affinity to N-terminal His6-tagged human SETDB1 Tudor domain (197 to 403 residues) expressed in Escherichia coli BL21(DE3)-pRARE2 cells assessed as induction of HSQC shift at 5 mM by 1H-15 N HSQC-TROSY NMR spectroscopy | Homo sapiens | 6 | ALA4385651 | cell-based format | Scientific Literature | |
| 18. | ALA4387485 | B | Binding affinity to N-terminally biotinylated human SETDB1 Tudor domain (197 to 403 residues) expressed in Escherichia coli BL21(DE3)-pRARE2 cells by SPR analysis | Homo sapiens | 8 | ALA4385651 | cell-based format | Scientific Literature | |
| 19. | ALA4387486 | B | Binding affinity to N-terminal His6-tagged human SETDB1 Tudor domain (197 to 403 residues) expressed in Escherichia coli BL21(DE3)-pRARE2 cells by ITC assay | Homo sapiens | 2 | ALA4385651 | cell-based format | Scientific Literature | |
| 20. | ALA4416353 | A | Inhibition of human SETDB1 expressed in sf9 insect cells assessed as reduction in methylated histone H3 full length level using histone H3 full length as substrate in presence of [3H] SAM incubated for 30 mins by scintillation counting | Homo sapiens | 1 | ALA4414609 | cell-based format | Scientific Literature |
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