# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3819943 | B | Activation of TREK2 (unknown origin) expressed in Xenopus oocytes assessed as increase in channel currents | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
2. | ALA3819961 | B | Inhibition of of TREK2 (unknown origin) expressed in oocytes assessed as reduction in channel currents | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA3819962 | B | Inhibition of of TREK2 (unknown origin) expressed in HEK293 cells assessed as reduction in channel currents | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
4. | ALA3993365 | B | Agonist activity at TREK-2 (unknown origin) expressed in HEK293 cells assessed as increase in K+ current at 100 uM measured at +60 mV by whole-cell patch clamp method relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
5. | ALA3993366 | B | Agonist activity at TREK-2 (unknown origin) expressed in HEK293 cells assessed as increase in K+ current at 20 uM measured at +60 mV by whole-cell patch clamp method relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA3993367 | B | Agonist activity at TREK-2 (unknown origin) expressed in HEK293 cells assessed as increase in K+ current at 10 uM measured at +60 mV by whole-cell patch clamp method relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
7. | ALA4419084 | B | Activation of K2P10.1 (unknown origin) expressed in Xenopus oocytes assessed as effect on channel currents at -80 mV holding potential by two-electrode voltage clamp assay | Homo sapiens | 2 | cell-based format | Patent Bioactivity Data | ||
8. | ALA4419087 | B | Activation of K2P10.1 (unknown origin) expressed in Xenopus oocytes assessed as effect on channel currents at 100 uM at -80 mV holding potential by two-electrode voltage clamp assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
9. | ALA4419103 | B | Activation of K2P10.1 (unknown origin) expressed in Xenopus oocytes assessed as effect on channel currents at 500 uM at -80 mV holding potential by two-electrode voltage clamp assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
10. | ALA4419104 | B | Activation of K2P10.1 (unknown origin) expressed in Xenopus oocytes assessed as effect on channel currents at -80 mV holding potential by two-electrode voltage clamp assay relative to control | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
11. | ALA4421811 | B | Activation of K2P10.1 (unknown origin) expressed in Xenopus oocytes assessed as effect on channel currents at -80 mV holding potential by two-electrode voltage clamp assay | Homo sapiens | 2 | cell-based format | Patent Bioactivity Data | ||
12. | ALA4421814 | B | Activation of K2P10.1 (unknown origin) expressed in Xenopus oocytes assessed as effect on channel currents at -80 mV holding potential at 100 uM by two-electrode voltage clamp assay relative to control | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
13. | ALA4421853 | B | Activation of K2P10.1 (unknown origin) expressed in Xenopus oocytes assessed as effect on channel currents at 500 uM at -80 mV holding potential by two-electrode voltage clamp assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
14. | ALA4421858 | B | Activation of K2P10.1 (unknown origin) expressed in Xenopus oocytes assessed as effect on channel currents at -80 mV holding potential by two-electrode voltage clamp assay relative to control | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
15. | ALA4667323 | B | Activation of human TREK2 by thallium flux mobilization assay | Homo sapiens | 21 | single protein format | Scientific Literature | ||
16. | ALA4667325 | B | Activation of human TREK2 at 30 uM by thallium flux mobilization assay relative to control | Homo sapiens | 33 | single protein format | Scientific Literature | ||
17. | ALA4667326 | B | Activation of human TREK2 at 10 uM by thallium flux mobilization assay relative to control | Homo sapiens | 4 | single protein format | Scientific Literature | ||
18. | ALA4670291 | B | Inhibition of human TREK2 at intermediate transition state expressed in CHO cells by whole-cell patch-clamp electrophysiological method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
19. | ALA5100509 | B | Inhibition of human TREK-2 expressed in Xenopus laevis oocytes assessed as inhibition of channel current at 10 uM at +40mV holding potential by two-electrode voltage clamp assay | Homo sapiens | 1 | cell-based format | Scientific Literature |