| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2343322 | B | Inhibition of TMPRSS4 in human SW480 cells assessed as inhibition of cell invasion at 0.1 uM relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 2. | ALA2343323 | B | Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Escherichia coli BL21 (DE3) using Z-Phe-Arg-7-amido-4-methylcoumarin hydrochloride as substrate by fluorometric analysis | Homo sapiens | 41 | assay format | Scientific Literature | ||
| 3. | ALA4418123 | B | Inhibition of TMPRSS4 serine protease domain (Val 205 to Leu 437 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) at 100 uM using Bac-Gln-Ala-Arg-7-amido-4-methylcoumarin hydrochloride substrate and measured for 5 mins at 5 mins intervals by fluorescence based assay relative to control | Homo sapiens | 66 | assay format | Patent Bioactivity Data | ||
| 4. | ALA4418124 | B | Inhibition of TMPRSS4 serine protease domain (Val 205 to Leu 437 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) at 30 uM using Bac-Gln-Ala-Arg-7-amido-4-methylcoumarin hydrochloride substrate and measured for 5 mins at 5 mins intervals by fluorescence based assay relative to control | Homo sapiens | 66 | assay format | Patent Bioactivity Data | ||
| 5. | ALA4418125 | B | Inhibition of TMPRSS4 serine protease domain (Val 205 to Leu 437 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) at 10 uM using Bac-Gln-Ala-Arg-7-amido-4-methylcoumarin hydrochloride substrate and measured for 5 mins at 5 mins intervals by fluorescence based assay relative to control | Homo sapiens | 66 | assay format | Patent Bioactivity Data | ||
| 6. | ALA4418126 | B | Inhibition of TMPRSS4 serine protease domain (Val 205 to Leu 437 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) using Bac-Gln-Ala-Arg-7-amido-4-methylcoumarin hydrochloride substrate and measured for 5 mins at 5 mins intervals by fluorescence based assay relative to control | Homo sapiens | 66 | assay format | Patent Bioactivity Data | ||
| 7. | ALA4418127 | B | Inhibition of TMPRSS4 (unknown origin) expressed in human SW480 cells assessed as reduction in cell migration at 0.8 uM incubated for 48 hrs by crystal violet staining based assay relative to control | Homo sapiens | 5 | cell-based format | Patent Bioactivity Data | ||
| 8. | ALA4418128 | B | Inhibition of TMPRSS4 (unknown origin) expressed in human SW480 cells assessed as reduction in cell migration at 2 uM incubated for 48 hrs by crystal violet staining based assay relative to control | Homo sapiens | 3 | cell-based format | Patent Bioactivity Data | ||
| 9. | ALA4418129 | B | Inhibition of TMPRSS4 (unknown origin) expressed in human SW480 cells assessed as reduction in cell migration at 25 uM incubated for 48 hrs by crystal violet staining based assay relative to control | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 10. | ALA4418130 | B | Inhibition of TMPRSS4 (unknown origin) expressed in human SW480 cells assessed as reduction in cell migration at 5 uM incubated for 48 hrs by crystal violet staining based assay relative to control | Homo sapiens | 2 | cell-based format | Patent Bioactivity Data | ||
| 11. | ALA4418542 | B | Inhibition of TMPRSS4 serine protease domain (Val205 to Leu437 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) at 1 mM using Boc-Gln-Ala-Arg-7-amido-4-methylcoumarin hydrochloride substrate measured at 5 mins intervals | Homo sapiens | 1 | assay format | Patent Bioactivity Data | ||
| 12. | ALA4418543 | B | Inhibition of TMPRSS4 serine protease domain (Val205 to Leu437 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) at 100 uM using Z-Phe-Arg7-amido-4-methylcoumarin hydrochloride substrate measured at 5 mins interval for 150 mins by fluorescence based assay relative to control | Homo sapiens | 75 | assay format | Patent Bioactivity Data | ||
| 13. | ALA4418544 | B | Inhibition of TMPRSS4 serine protease domain (Val205 to Leu437 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) at 30 uM using Z-Phe-Arg7-amido-4-methylcoumarin hydrochloride substrate measured at 5 mins interval for 150 mins by fluorescence based assay relative to control | Homo sapiens | 75 | assay format | Patent Bioactivity Data | ||
| 14. | ALA4418545 | B | Inhibition of TMPRSS4 serine protease domain (Val205 to Leu437 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) at 10 uM using Z-Phe-Arg7-amido-4-methylcoumarin hydrochloride substrate measured at 5 mins interval for 150 mins by fluorescence based assay relative to control | Homo sapiens | 75 | assay format | Patent Bioactivity Data | ||
| 15. | ALA4418546 | B | Inhibition of TMPRSS4 (unknown origin) expressed in human SW480 cells assessed as reduction in cell infiltration at 0.8 uM incubated for 48 hrs by crystal violet staining based assay relative to control | Homo sapiens | 5 | cell-based format | Patent Bioactivity Data | ||
| 16. | ALA4418547 | B | Inhibition of TMPRSS4 (unknown origin) expressed in human SW480 cells assessed as reduction in cell infiltration at 2 uM incubated for 48 hrs by crystal violet staining based assay relative to control | Homo sapiens | 3 | cell-based format | Patent Bioactivity Data | ||
| 17. | ALA4418548 | B | Inhibition of TMPRSS4 (unknown origin) expressed in human SW480 cells assessed as reduction in cell infiltration at 0.1 uM incubated for 48 hrs by crystal violet staining based assay relative to control | Homo sapiens | 5 | cell-based format | Patent Bioactivity Data | ||
| 18. | ALA4418549 | B | Inhibition of TMPRSS4 (unknown origin) expressed in human SW480 cells assessed as reduction in cell infiltration at 25 uM incubated for 48 hrs by crystal violet staining based assay relative to control | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 19. | ALA4418550 | B | Inhibition of TMPRSS4 (unknown origin) expressed in human SW480 cells assessed as reduction in cell infiltration at 5 uM incubated for 48 hrs by crystal violet staining based assay relative to control | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 20. | ALA4418551 | B | Inhibition of TMPRSS4 (unknown origin) expressed in human SW480 cells assessed as reduction in cell infiltration at 1 uM incubated for 48 hrs by crystal violet staining based assay relative to control | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data |
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