# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1220763 | Binding | Inhibition of KDR in zebrafish assessed as embryonic axis dorsalization at 10 uM treated occasionally at 6 to 8 hrs post-fertilization measured at 48 hrs | Danio rerio | 1 | ALA1212693 | single protein format | Scientific Literature | |
2. | ALA1226445 | Binding | Inhibition of VEGFR2-mediated regenerative angiogenesis in adult zebrafish tail fin vessel harboring hypomorphic mutation in grlm145 gene assessed as vascularization of newly generated tissues at 100 nM measured on day 3 post treatment by angiography | Danio rerio | 1 | ALA1221183 | tissue-based format | Scientific Literature | |
3. | ALA1226446 | Binding | Partial inhibition of VEGFR2-mediated regenerative angiogenesis in adult zebrafish tail fin vessel at 100 nM after 3 days by microscopy | Danio rerio | 1 | ALA1221183 | single protein format | Scientific Literature | |
4. | ALA1226447 | Binding | Complete inhibition of VEGFR2-mediated regenerative angiogenesis in adult zebrafish tail fin vessel at 500 nM after 3 days by microscopy | Danio rerio | 1 | ALA1221183 | single protein format | Scientific Literature | |
5. | ALA1226448 | Binding | Ratio of inhibition of VEGFR2-mediated regenerative angiogenesis in embryonic zebrafish to adult zebrafish tail fin vessel | Danio rerio | 1 | ALA1221183 | single protein format | Scientific Literature | |
6. | ALA1226449 | Binding | Inhibition of VEGFR2-mediated regenerative angiogenesis in adult zebrafish tail fin distal vessel at 500 nM treated for 3 days post 5 days of amputation period measured on day 5 by angiography | Danio rerio | 1 | ALA1221183 | tissue-based format | Scientific Literature | |
7. | ALA1226450 | Binding | Inhibition of VEGFR2-mediated regenerative angiogenesis in adult zebrafish tail fin proximal vessel at 500 nM treated for 3 days post 5 days of amputation period measured on day 5 by angiography | Danio rerio | 1 | ALA1221183 | tissue-based format | Scientific Literature | |
8. | ALA1226451 | Binding | Inhibition of VEGFR2-mediated regenerative angiogenesis in adult zebrafish tail fin distal vessel at 500 nM treated for 3 days post 5 days of amputation period measured on day 8 by angiography | Danio rerio | 1 | ALA1221183 | tissue-based format | Scientific Literature | |
9. | ALA1226452 | Binding | Inhibition of VEGFR2-mediated regenerative angiogenesis in adult zebrafish tail fin proximal vessel at 500 nM treated for 3 days post 5 days of amputation period measured on day 8 by angiography | Danio rerio | 1 | ALA1221183 | tissue-based format | Scientific Literature | |
10. | ALA1226453 | Binding | Inhibition of VEGFR2-mediated VEGFA mRNA expression in adult zebrafish tail fin at 500 uM after 1.5 days by in-situ hybridization assay | Danio rerio | 1 | ALA1221183 | tissue-based format | Scientific Literature | |
11. | ALA1226454 | Binding | Inhibition of VEGFR2-mediated msxb mRNA expression in adult zebrafish tail fin at 500 uM measured on day 2 post treatment by in-situ hybridization assay | Danio rerio | 1 | ALA1221183 | tissue-based format | Scientific Literature | |
12. | ALA1226455 | Binding | Inhibition of VEGFR2-mediated shh mRNA expression in adult zebrafish tail fin at 500 uM measured on day 2 post treatment by in-situ hybridization assay | Danio rerio | 1 | ALA1221183 | tissue-based format | Scientific Literature | |
13. | ALA1226458 | Binding | Inhibition of VEGFR2-mediated regenerative angiogenesis in adult zebrafish tail fin assessed as amount of tissue regeneration at 500 nM measured on day 7 post treatment by angiography | Danio rerio | 1 | ALA1221183 | tissue-based format | Scientific Literature | |
14. | ALA1226459 | Binding | Inhibition of VEGFR2-mediated regenerative angiogenesis in adult zebrafish tail fin assessed as amount of tissue regeneration at 500 nM measured on day 14 post treatment by angiography | Danio rerio | 1 | ALA1221183 | tissue-based format | Scientific Literature | |
15. | ALA1226460 | Binding | Inhibition of VEGFR2-mediated regenerative angiogenesis in adult zebrafish tail fin at 500 nM treated for 3 days measured after 4 days of drug washout by angiography | Danio rerio | 1 | ALA1221183 | tissue-based format | Scientific Literature | |
16. | ALA1226462 | Binding | Inhibition of VEGFR2-mediated regenerative angiogenesis in adult zebrafish tail fin assessed as reduction of plexus formation at 500 nM treated for 3 days measured after 4 days of drug washout by angiography | Danio rerio | 1 | ALA1221183 | tissue-based format | Scientific Literature | |
17. | ALA1226463 | Binding | Effect on VEGFR2-mediated VEGFA mRNA expression in adult zebrafish tail fin assessed as VEGFA level at 500 uM after 3 days by real-time PCR analysis relative to control | Danio rerio | 1 | ALA1221183 | assay format | Scientific Literature | |
18. | ALA1226519 | Binding | Effect on VEGFR2-mediated VEGFA mRNA expression in adult zebrafish tail fin at 500 uM treated for 3 days measured on day 5 following drug washout by real-time PCR analysis | Danio rerio | 1 | ALA1221183 | assay format | Scientific Literature | |
19. | ALA1226521 | Binding | Inhibition of VEGFR2-mediated regenerative angiogenesis in adult zebrafish tail fin assessed as decrease in tissue regeneration at 500 nM after 5 days by angiography | Danio rerio | 1 | ALA1221183 | tissue-based format | Scientific Literature | |
20. | ALA1226522 | Binding | Effect on VEGFR2-mediated axonal outgrowth in adult zebrafish tail fin at 500 nM after 5 days by zn-12 staining-based immunohistochemistry | Danio rerio | 1 | ALA1221183 | single protein format | Scientific Literature |