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# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1287076 | Binding | Inhibition of human myeloperoxidase at 10 uM | Homo sapiens | 1 | ALA1275350 | single protein format | Scientific Literature | |
2. | ALA1640944 | Binding | Inhibition of recombinant MPO assessed as rate of electron donation to MPO redox intermediate compound I by sequential mixing stopped flow spectroscopy | 2 | ALA1629449 | single protein format | Scientific Literature | ||
3. | ALA1640945 | Binding | Inhibition of recombinant MPO mediated taurine chlorination by microplate reader method | 24 | ALA1629449 | tissue-based format | Scientific Literature | ||
4. | ALA1640946 | Binding | Inhibition of recombinant MPO mediated LDL oxidation using MPO/Cl-/H2O2 system | 24 | ALA1629449 | single protein format | Scientific Literature | ||
5. | ALA1640947 | Binding | Inhibition of recombinant MPO assessed as rate of electron donation to MPO redox intermediate compound II by sequential mixing stopped flow spectroscopy | 2 | ALA1629449 | single protein format | Scientific Literature | ||
6. | ALA1027367 | Binding | Inhibition of MPO activity in TNF-alpha-stimulated human HL60 cells measured enzyme activity per 10'6 cells by spectrophotometrically | Homo sapiens | 2 | ALA1152752 | cell-based format | Scientific Literature | |
7. | ALA1027368 | Binding | Inhibition of MPO activity in TNF-alpha-stimulated human HL60 cells measured enzyme activity per 10'6 cells at 10 uM by spectrophotometrically | Homo sapiens | 2 | ALA1152752 | cell-based format | Scientific Literature | |
8. | ALA1027369 | Binding | Inhibition of MPO activity in TNF-alpha-stimulated human HL60 cells measured enzyme activity per 10'6 cells at 50 uM by spectrophotometrically | Homo sapiens | 2 | ALA1152752 | cell-based format | Scientific Literature | |
9. | ALA840669 | Functional | Ability to inhibit C5a-induced release of azurophilic granular constituent myeloperoxidase (MPO) from intact neutrophils | 1 | ALA1126141 | assay format | Scientific Literature | ||
10. | ALA841524 | Functional | Compound was tested for the induction of nonspecific myeloperoxidase (MPO) release | 5 | ALA1126141 | assay format | Scientific Literature | ||
11. | ALA750554 | Functional | In vivo agonist efficacy as the maximal lysosomal myeloperoxidase (MPO) release in PMNL assay | 5 | ALA1126196 | organism-based format | Scientific Literature | ||
12. | ALA750555 | Functional | In vivo agonist efficacy was determined as the maximal lysosomal myeloperoxidase (MPO) release in PMNL assay. | 11 | ALA1126196 | organism-based format | Scientific Literature | ||
13. | ALA750556 | Functional | In vivo potency as the maximal lysosomal myeloperoxidase (MPO) release in PMNL assay | 5 | ALA1126196 | organism-based format | Scientific Literature | ||
14. | ALA750557 | Functional | In vivo potency was determined as the maximal lysosomal myeloperoxidase (MPO) release in PMNL assay. | 11 | ALA1126196 | organism-based format | Scientific Literature | ||
15. | ALA750770 | Functional | Compound was evaluated for the inhibition of serum-opsonized zymosan stimulated myeloperoxidase release from human neutrophil | Homo sapiens | 1 | ALA1126285 | assay format | Scientific Literature | |
16. | ALA750777 | Functional | Tested in vivo for the ability to inhibit myeloperoxidase (MPO) activity in the colon of the TNB/ethanol-induced chronic colitis rats at the dosage of 100 mg/kg/day | Rattus norvegicus | 6 | ALA1127462 | organism-based format | Scientific Literature | |
17. | ALA750778 | Functional | Tested in vivo for the ability to inhibit myeloperoxidase (MPO) activity in the colon of the TNB/ethanol-induced chronic colitis rats at the dosage of 500 mg/kg/day | Rattus norvegicus | 1 | ALA1127462 | organism-based format | Scientific Literature | |
18. | ALA931190 | Binding | Inhibition of chlorinating activity of recombinant myeloperoxidase by taurine assay | 13 | ALA1141613 | tissue-based format | Scientific Literature | ||
19. | ALA932250 | Binding | Inhibition of chlorinating activity of recombinant myeloperoxidase at 0.5 uM by taurine assay | 12 | ALA1141613 | tissue-based format | Scientific Literature | ||
20. | ALA932251 | Binding | Inhibition of chlorinating activity of recombinant myeloperoxidase at 1 uM by taurine assay | 12 | ALA1141613 | tissue-based format | Scientific Literature |
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