# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2354178 | B | Induction of internalization of Frizzled1-GFP (unknown origin) expressed in human U2OS cells at 12.5 uM after 6 hrs by confocal microscopy | Homo sapiens | 23 | ALA2346499 | cell-based format | Scientific Literature | |
2. | ALA4276087 | F | Induction of GFP-tagged Fzd1 (unknown origin) internalization expressed in human U2OS cells at 12.5 after 6 hrs by confocal microscopic method | Homo sapiens | 2 | ALA4270654 | cell-based format | Scientific Literature | |
3. | ALA4372846 | B | Induction of GFP-tagged Fzd1 (unknown origin) internalization expressed in human U2OS cells at 12.5 after 6 hrs by confocal microscopic method relative to control | Homo sapiens | 9 | ALA4371061 | cell-based format | Scientific Literature | |
4. | ALA4376172 | B | Binding affinity to recombinant human Frizzled-1 (Gln73 to His253 residues)/human IgG1 chimeric protein expressed in mouse NS0 cells by SPR assay | Homo sapiens | 3 | ALA4373723 | cell-based format | Scientific Literature | |
5. | ALA4807085 | F | Antagonist activity at Wnt3a-stimulated frizzled-1 (unknown origin) expressed in human HEK293superTOP flash cells incubated for 24 hrs by luciferase reporter gene assay | Homo sapiens | 8 | ALA4806959 | cell-based format | Patent Bioactivity Data | |
6. | ALA4807087 | F | Agonist activity at frizzled-1 (unknown origin) expressed in human HEK293superTOP flash cells by luciferase reporter gene assay | Homo sapiens | 8 | ALA4806959 | cell-based format | Patent Bioactivity Data | |
7. | ALA4807092 | F | Antagonist activity at frizzled-1 (unknown origin) expressed in rat C-FIT cells assessed as inhibition of Wnt3a-stimulated blockade of migration at 10 nM incubated for 48 hrs and measured for 24 hrs following the scratch by scratch wound healing assay | Homo sapiens | 1 | ALA4806959 | cell-based format | Patent Bioactivity Data | |
8. | ALA4807098 | F | Antagonist activity at frizzled-1 (unknown origin) expressed in rat C-FIT cells assessed as inhibition of Wnt3a-stimulated cell differentiation changes by measuring alpha-smooth muscle actin gene expression at 10 nM by quantitative RT-PCR analysis | Homo sapiens | 1 | ALA4806959 | cell-based format | Patent Bioactivity Data | |
9. | ALA4807099 | F | Antagonist activity at frizzled-1 (unknown origin) expressed in rat C-FIT cells assessed as inhibition of Wnt5a-stimulated cell differentiation changes by measuring alpha-smooth muscle actin gene expression at 10 nM by quantitative RT-PCR analysis | Homo sapiens | 1 | ALA4806959 | cell-based format | Patent Bioactivity Data | |
10. | ALA4807125 | F | Antagonist activity at Wnt3a-stimulaed frizzled-1 (unknown origin) expressed in human HEK293superTOP flash cells at 1 nM incubated for 24 hrs by luciferase reporter gene assay (Rvb = 0%) | Homo sapiens | 17 | ALA4806959 | cell-based format | Patent Bioactivity Data | |
11. | ALA4807184 | F | Antagonist activity at Wnt3a-stimulaed human frizzled-1 expressed in human HEK293superTOP flash cells incubated for 24 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA4806959 | cell-based format | Patent Bioactivity Data | |
12. | ALA4807189 | F | Antagonist activity at Wnt3a-stimulated frizzled-1 (unknown origin) expressed in human HEK293superTOP flash cells at 10 nM incubated for 24 hrs by luciferase reporter gene assay | Homo sapiens | 16 | ALA4806959 | cell-based format | Patent Bioactivity Data | |
13. | ALA4807421 | F | Antagonist activity at Wnt3a-stimulated frizzled-1 (unknown origin) expressed in human HEK293superTOP flash cells incubated for 24 hrs by luciferase reporter gene assay | Homo sapiens | 8 | ALA4806963 | cell-based format | Patent Bioactivity Data | |
14. | ALA4807423 | F | Agonist activity at frizzled-1 (unknown origin) expressed in human HEK293superTOP flash cells by luciferase reporter gene assay | Homo sapiens | 8 | ALA4806963 | cell-based format | Patent Bioactivity Data | |
15. | ALA4807428 | F | Antagonist activity at frizzled-1 (unknown origin) expressed in rat C-FIT cells assessed as inhibition of Wnt3a-stimulated blockade of migration at 10 nM incubated for 48 hrs and measured for 24 hrs following the scratch by scratch wound healing assay | Homo sapiens | 1 | ALA4806963 | cell-based format | Patent Bioactivity Data | |
16. | ALA4807434 | F | Antagonist activity at frizzled-1 (unknown origin) expressed in rat C-FIT cells assessed as inhibition of Wnt3a-stimulated cell differentiation changes by measuring alpha-smooth muscle actin gene expression at 10 nM by quantitative RT-PCR analysis | Homo sapiens | 1 | ALA4806963 | cell-based format | Patent Bioactivity Data | |
17. | ALA4807435 | F | Antagonist activity at frizzled-1 (unknown origin) expressed in rat C-FIT cells assessed as inhibition of Wnt5a-stimulated cell differentiation changes by measuring alpha-smooth muscle actin gene expression at 10 nM by quantitative RT-PCR analysis | Homo sapiens | 1 | ALA4806963 | cell-based format | Patent Bioactivity Data | |
18. | ALA4807461 | F | Antagonist activity at Wnt3a-stimulaed frizzled-1 (unknown origin) expressed in human HEK293superTOP flash cells at 1 nM incubated for 24 hrs by luciferase reporter gene assay (Rvb = 0%) | Homo sapiens | 17 | ALA4806963 | cell-based format | Patent Bioactivity Data | |
19. | ALA4807522 | F | Antagonist activity at Wnt3a-stimulaed human frizzled-1 expressed in human HEK293superTOP flash cells incubated for 24 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA4806963 | cell-based format | Patent Bioactivity Data | |
20. | ALA4807526 | F | Antagonist activity at Wnt3a-stimulated frizzled-1 (unknown origin) expressed in human HEK293superTOP flash cells at 10 nM incubated for 24 hrs by luciferase reporter gene assay | Homo sapiens | 16 | ALA4806963 | cell-based format | Patent Bioactivity Data |