| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2354206 | F | PubChem BioAssay. Luminescence-based cell-based high throughput dose response assay to identify activators of the function of SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (SMARCA2, BRM). (Class of assay: confirmatory) | 228 | cell-based format | PubChem BioAssays | |||
| 2. | ALA3383429 | B | Inhibition of human SMARCA2 by BROMOscan assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 3. | ALA3773279 | B | Binding affinity to biotinylated SMARCA2 (unknown origin) expressed in Escherichia coli at 0.2 to 1 uM by Biolayer Interferometric analysis | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 4. | ALA3773295 | B | Binding affinity to SMARCA2 in human HUT78 cell extract by chemoproteomic competition binding assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA3777041 | B | Inhibition of recombinant human SMARCA2 expressed in bacterial system assessed as residual activity at 1 uM by bromoscan assay relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 6. | ALA3790869 | B | Binding affinity to SMARCA2 (unknown origin) at 10 uM by DFS analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA3821762 | B | Binding affinity to human SMARC2A expressed in BL21 (DE3)-R3-BirA cells assessed as change in melting temperature at 10 uM by sypro-orange dye-based differential scanning fluorimetric analysis | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 8. | ALA3821763 | B | Binding affinity to human SMARC2B expressed in BL21 (DE3)-R3-BirA cells assessed as change in melting temperature at 10 uM by sypro-orange dye-based differential scanning fluorimetric analysis | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 9. | ALA3821769 | B | Inhibition of chromatin binding to full length GFP-tagged wild type SMARCA2 expressed in human U2OS cells assessed as acceleration of FRAP half-recovery time incubated for 1 hr in presence of SAHA by FRAP assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA3822103 | B | Binding affinity to human SMARCA2 expressed in BL21 (DE3)-R3-BirA cells by isothermal titration calorimetry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA3825728 | B | Binding affinity to His6-tagged human recombinant SMARCA2B bromodomain expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells by VP-ITC microcalorimetry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA3825732 | B | Binding affinity to His6-tagged human recombinant SMARCA2A bromodomain expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells assessed as change in melting temperature at 10 uM by SyproOrange dye based DSF thermal shift assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 13. | ALA3825733 | B | Binding affinity to His6-tagged human recombinant SMARCA2B bromodomain expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells assessed as change in melting temperature at 10 uM by SyproOrange dye based DSF thermal shift assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 14. | ALA3825928 | B | Inhibition of GFP-fused N-terminal full length human recombinant Wild type SMARCA2 transfected in human U2OS cells assessed as displacement of SMARCA2 from chromatin by measuring FRAP recovery time at 1 to 5 uM by laser scanning inverted microscopy relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA3863016 | B | Binding affinity to SMARCA 2A (unknown origin) assessed as change in melting temperature at 100 uM by differential scanning fluorimetric assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 16. | ALA3863025 | B | Binding affinity to SMARCA 2A (unknown origin) at 15 uM by ITC method | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 17. | ALA4012423 | B | Inhibition of SMARCA2 (unknown origin) at 100 uM using acetylated lysine as substrate relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 18. | ALA4012427 | B | Inhibition of SMARCA2 (unknown origin) at 50 uM using acetylated lysine as substrate relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 19. | ALA4016234 | B | Inhibition of human SMARCA2 bromodomain (1337 to 1486 residues) expressed bacterial expression system at 20 uM by bromoscan assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 20. | ALA4020266 | B | Inhibition of human SMARCA2 (S1377 to Q1486 residues) expressed in bacterial expression system at 1 uM by BROMOscan assay | Homo sapiens | 1 | assay format | Scientific Literature |
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