| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3998488 | B | Antagonist activity at recombinant human glycine receptor alpha 1 beta expressed in human tsA201 cells assessed as inhibition of glycine-induced receptor activation after 30 mins by FLIPR membrane potential blue assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 2. | ALA3998490 | B | Antagonist activity at recombinant human glycine receptor alpha 1 beta expressed in HEK293 cells assessed as inhibition of glycine-induced current at -50mV holding potential by whole cell patch-clamp method | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 3. | ALA4219611 | B | Inhibition of recombinant human glycine receptor alpha1beta expressed in HEK293 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4219620 | B | Positive allosteric modulation of human glycine alpha1beta receptor expressed in HEK293T cells assessed as glycine-induced increase in current response after 18 to 24 hrs by membrane potential blue dye based FLIPR assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA4219929 | B | Positive allosteric modulation of human GlyRalpha1beta expressed in HEK293 cells assessed as potentiation of glycine-induced calcium flux by calcium dye-5 based FLIPR assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4219935 | B | Positive allosteric modulation of human GlyRalpha1beta expressed in HEK293 cells assessed as potentiation of glycine-induced calcium flux by calcium dye-5 based FLIPR assay relative to glycine | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4252017 | B | Positive allosteric modulation of human GlyRalpha1beta assessed as increase in glycine-induced chloride ion flux by FLIPR assay | Homo sapiens | 2 | protein complex format | Scientific Literature | ||
| 8. | ALA4342370 | B | Antagonist activity at human glycine receptor subunit alpha-1beta expressed in human tsA201 cells assessed as reduction in glycine-induced response by fluorescence-based FLIPR membrane potential blue assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA4342372 | B | Antagonist activity at human glycine receptor subunit alpha-1beta expressed in HEK293 cells assessed as reduction in glycine-induced whole cell currents by patch-clamp technique | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA4820882 | B | Antagonist activity at human glycine receptor subunit alpha-1beta expressed in human tsA201 cells assessed as reduction in glycine-induced response incubated for 30 mins by fluorescence-based FLIPR membrane potential blue assay | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
| 11. | ALA4820884 | B | Antagonist activity at human glycine receptor subunit alpha-1beta expressed in HEK293 cells assessed as reduction in glycine-induced currents by whole-cell patch-clamp assay | Homo sapiens | 4 | cell-based format | Scientific Literature |
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