# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA615727 | F | Antagonistic activity at postsynaptic 5-HT1A receptor was measured by its ability to inhibit hypothermia elicited by s.c. administration of 8-OH-DPAT in rat;ranges from (.26-3.52) | 1 | ALA1135394 | organism-based format | Scientific Literature | ||
2. | ALA615589 | B | Displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor of rat hippocampal membranes | Rattus norvegicus | 6 | ALA1129976 | cell membrane format | Scientific Literature | |
3. | ALA615859 | B | In vitro affinity towards 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT as radioligand in hippocampus | 31 | ALA1127849 | tissue-based format | Scientific Literature | ||
4. | ALA615785 | B | Concentration necessary to achieve half maximal inhibition of [3H]8-Hydroxy-2-(di-n-propylamino)tetralin binding to 5-hydroxytryptamine 1A receptor at 1 uM | 5 | ALA1124434 | single protein format | Scientific Literature | ||
5. | ALA615786 | F | Ability to inhibit 5-HT sensitive,forskolin-stimulated adenylyl cyclase(FSC) activity in rat hippocampal membranes mediated through 5-hydroxytryptamine 1A receptor | 2 | ALA1128704 | cell membrane format | Scientific Literature | ||
6. | ALA615787 | F | Agonistic activity (induction of forepaw treading in rats)on postsynaptic 5-hydroxytryptamine 1A receptor while iv administration | 1 | ALA1134307 | organism-based format | Scientific Literature | ||
7. | ALA615788 | F | Agonistic activity (induction of forepaw treading in rats)on postsynaptic 5-hydroxytryptamine 1A receptor while subcutaneous administration | 1 | ALA1134307 | organism-based format | Scientific Literature | ||
8. | ALA767044 | F | Inhibition of forskolin stimulated adenylate cyclase at 5-hydroxytryptamine 1A receptor | 6 | ALA1127604 | assay format | Scientific Literature | ||
9. | ALA615789 | F | Agonistic activity (induction of forepaw treading in rats)on postsynaptic 5-hydroxytryptamine 1A receptor while iv administration | 1 | ALA1134307 | organism-based format | Scientific Literature | ||
10. | ALA615790 | F | Agonistic activity (induction of forepaw treading in rats)on postsynaptic 5-hydroxytryptamine 1A receptor while subcutaneous administration | 1 | ALA1134307 | organism-based format | Scientific Literature | ||
11. | ALA615813 | F | Evaluated for the 5-hydroxytryptamine 1A receptor agonist activity in LY-293284 trained rats | 3 | ALA1133543 | assay format | Scientific Literature | ||
12. | ALA615814 | F | Percent of maximum response by 5-HT when tested for inhibition of vasoactive intestinal polypeptide-induced (VIP-induced) cAMP formation assessed in GH4ZD10 cells at 10 uM concentration | 3 | ALA1133455 | cell-based format | Scientific Literature | ||
13. | ALA615816 | F | Percent of maximum response by 5-HT when tested for inhibition of vasoactive intestinal polypeptide-induced (VIP-induced) cAMP formation assessed in GH4ZD10 cells at 50 uM concentration; No effect | 3 | ALA1133455 | cell-based format | Scientific Literature | ||
14. | ALA615817 | B | Binding affinity at [3H]8-OH-DPAT-Labeled 5-hydroxytryptamine 1A receptor sites in rat brain hippocampal membranes expressed as Hill values | 15 | ALA1124332 | cell membrane format | Scientific Literature | ||
15. | ALA615818 | B | Ability to bind at 5-hydroxytryptamine 1A receptor of rat hippocampus by displacing [3H]8-OH-DPAT | 4 | ALA1124475 | tissue-based format | Scientific Literature | ||
16. | ALA615819 | B | Ability to bind at serotonin 5-hydroxytryptamine 1A receptors of rat hippocampus by displacing [3H]8-OH-DPAT | 8 | ALA1124475 | tissue-based format | Scientific Literature | ||
17. | ALA615820 | B | Binding affinity against 5-hydroxytryptamine 1A receptor (5-HT1A) by displacement of [3H]8-OH-DPAT from rat hippocampus membranes | 80 | ALA1145929 | cell membrane format | Scientific Literature | ||
18. | ALA615821 | B | Binding affinity against 5-hydroxytryptamine 1A receptor of rat hippocampal tissue with [3H]8-OH-DPAT | Rattus norvegicus | 1 | ALA1125892 | tissue-based format | Scientific Literature | |
19. | ALA615822 | B | Binding affinity against 5-hydroxytryptamine 1A receptor of rat hippocampal tissue with [3H]5-HT | Rattus norvegicus | 1 | ALA1125892 | tissue-based format | Scientific Literature | |
20. | ALA615823 | B | Binding affinity against 5-hydroxytryptamine 1A receptor using in rat hippocampal tissue using [3H]8-OH-DPAT as radioligand | 7 | ALA1125892 | tissue-based format | Scientific Literature |