# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1262518 | F | Binding affinity to membrane of Propionibacterium acnes ATCC 6919 at 1 uM after 1 hr by fluorescence microscopy under anaerobic condition | Cutibacterium acnes | 1 | ALA1255316 | assay format | Scientific Literature | |
2. | ALA1262519 | F | Binding affinity to membrane of Propionibacterium acnes ATCC 6919 at 10 uM after 1 hr by fluorescence microscopy under anaerobic condition | Cutibacterium acnes | 2 | ALA1255316 | assay format | Scientific Literature | |
3. | ALA1639473 | B | Binding affinity to methicillin-susceptible Staphylococcus aureus 11/11 cell membrane assessed as amount of compound bound at 6 ug after 10 mins | Staphylococcus aureus | 1 | ALA1629699 | assay format | Scientific Literature | |
4. | ALA1639474 | B | Binding affinity to daptomycin-resistant Staphylococcus aureus REF2145 cell membrane assessed as amount of compound bound at 6 ug after 10 mins | Staphylococcus aureus | 1 | ALA1629699 | assay format | Scientific Literature | |
5. | ALA1639475 | B | Binding affinity to methicillin-susceptible Staphylococcus aureus 11/11 cell membrane assessed as amount of compound bound at 8 ug after 10 mins | Staphylococcus aureus | 1 | ALA1629699 | assay format | Scientific Literature | |
6. | ALA1639476 | B | Binding affinity to daptomycin-resistant Staphylococcus aureus REF2145 cell membrane assessed as amount of compound bound at 8 ug after 10 mins | Staphylococcus aureus | 1 | ALA1629699 | assay format | Scientific Literature | |
7. | ALA1667129 | B | Binding affinity to cell membrane of Bacillus subtilis JCM 1465 assessed as dissipation of nisin A-induced membrane potential | Bacillus subtilis | 1 | ALA1649563 | assay format | Scientific Literature | |
8. | ALA1667124 | B | Binding affinity to cell membrane of Staphylococcus aureus grown in MHB medium at 8 ug/ml by scintillation counting relative to control | Staphylococcus aureus | 1 | ALA1649547 | assay format | Scientific Literature | |
9. | ALA4150273 | B | Induction of cell membrane permeabilization in Mycobacterium bovis BCG ATCC 35734 at 4 times MIC90 after 12 hrs by SYTO9/propidium iodide staining-based fluorescence assay | Mycobacterium tuberculosis variant bovis BCG | 1 | ALA4145615 | assay format | Scientific Literature | |
10. | ALA4150274 | B | Induction of cell membrane permeabilization in Mycobacterium bovis BCG ATCC 35734 at 4 times MIC90 after 24 hrs by SYTO9/propidium iodide staining-based fluorescence assay | Mycobacterium tuberculosis variant bovis BCG | 1 | ALA4145615 | assay format | Scientific Literature | |
11. | ALA4150275 | B | Induction of cell membrane permeabilization in Mycobacterium bovis BCG ATCC 35734 at 4 times MIC90 after 48 hrs by SYTO9/propidium iodide staining-based fluorescence assay | Mycobacterium tuberculosis variant bovis BCG | 3 | ALA4145615 | assay format | Scientific Literature | |
12. | ALA4150291 | B | Disruption of cell membrane potential in Mycobacterium bovis BCG ATCC 35734 at 100 uM after 20 mins to 5 days by DiOC2 dye-based fluorescence assay | Mycobacterium tuberculosis variant bovis BCG | 1 | ALA4145615 | assay format | Scientific Literature | |
13. | ALA4150292 | B | Disruption of cell membrane potential in Mycobacterium bovis BCG ATCC 35734 at 0.08 uM after 20 mins to 5 days by DiOC2 dye-based fluorescence assay | Mycobacterium tuberculosis variant bovis BCG | 1 | ALA4145615 | assay format | Scientific Literature | |
14. | ALA4150293 | B | Disruption of cell membrane potential in Mycobacterium bovis BCG ATCC 35734 at 4 times MIC90 after 20 mins to 5 hrs by DiOC2 dye-based fluorescence assay | Mycobacterium tuberculosis variant bovis BCG | 3 | ALA4145615 | assay format | Scientific Literature | |
15. | ALA4150294 | B | Disruption of cell membrane potential in Mycobacterium bovis BCG ATCC 35734 at 4 times MIC90 after 3 to 5 days by DiOC2 dye-based fluorescence assay | Mycobacterium tuberculosis variant bovis BCG | 3 | ALA4145615 | assay format | Scientific Literature | |
16. | ALA4150295 | B | Disruption of cell membrane potential in Mycobacterium bovis BCG ATCC 35734 at 4 times MIC90 after 4 hrs by DiOC2 dye-based fluorescence assay | Mycobacterium tuberculosis variant bovis BCG | 1 | ALA4145615 | assay format | Scientific Literature | |
17. | ALA4150296 | B | Disruption of cell membrane potential in Mycobacterium bovis BCG ATCC 35734 at 4 times MIC90 after 3 days by DiOC2 dye-based fluorescence assay | Mycobacterium tuberculosis variant bovis BCG | 1 | ALA4145615 | assay format | Scientific Literature | |
18. | ALA4260165 | B | Binding affinity to methicillin resistant Staphylococcus aureus cell membrane assessed as induction of membrane permeabilization at 12 times MIC measured for 10 to 70 mins by propidium iodide dye based fluorescence assay | Staphylococcus aureus | 1 | ALA4257553 | assay format | Scientific Literature | |
19. | ALA4414061 | B | Binding affinity to bacterial cell membrane assessed as Ka1 by SPR assay | Bacteria | 3 | ALA4411332 | cell membrane format | Scientific Literature | |
20. | ALA4414062 | B | Binding affinity to bacterial cell membrane assessed as Kd1 by SPR assay | Bacteria | 3 | ALA4411332 | cell membrane format | Scientific Literature |