| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1262518 | F | Binding affinity to membrane of Propionibacterium acnes ATCC 6919 at 1 uM after 1 hr by fluorescence microscopy under anaerobic condition | Cutibacterium acnes | 1 | assay format | Scientific Literature | ||
| 2. | ALA1262519 | F | Binding affinity to membrane of Propionibacterium acnes ATCC 6919 at 10 uM after 1 hr by fluorescence microscopy under anaerobic condition | Cutibacterium acnes | 2 | assay format | Scientific Literature | ||
| 3. | ALA1639473 | B | Binding affinity to methicillin-susceptible Staphylococcus aureus 11/11 cell membrane assessed as amount of compound bound at 6 ug after 10 mins | Staphylococcus aureus | 1 | assay format | Scientific Literature | ||
| 4. | ALA1639474 | B | Binding affinity to daptomycin-resistant Staphylococcus aureus REF2145 cell membrane assessed as amount of compound bound at 6 ug after 10 mins | Staphylococcus aureus | 1 | assay format | Scientific Literature | ||
| 5. | ALA1639475 | B | Binding affinity to methicillin-susceptible Staphylococcus aureus 11/11 cell membrane assessed as amount of compound bound at 8 ug after 10 mins | Staphylococcus aureus | 1 | assay format | Scientific Literature | ||
| 6. | ALA1639476 | B | Binding affinity to daptomycin-resistant Staphylococcus aureus REF2145 cell membrane assessed as amount of compound bound at 8 ug after 10 mins | Staphylococcus aureus | 1 | assay format | Scientific Literature | ||
| 7. | ALA1667129 | B | Binding affinity to cell membrane of Bacillus subtilis JCM 1465 assessed as dissipation of nisin A-induced membrane potential | Bacillus subtilis | 1 | assay format | Scientific Literature | ||
| 8. | ALA1667124 | B | Binding affinity to cell membrane of Staphylococcus aureus grown in MHB medium at 8 ug/ml by scintillation counting relative to control | Staphylococcus aureus | 1 | assay format | Scientific Literature | ||
| 9. | ALA5255983 | B | Disruption of membrane integrity in Staphylococcus aureus ATCC 29213 assessed as cell membrane damage at 5 x MIC incubated for 2 hrs by propidium iodide staining based assay | Staphylococcus aureus | 1 | subcellular format | Scientific Literature | ||
| 10. | ALA5255984 | B | Disruption of membrane integrity in Staphylococcus aureus ATCC 29213 assessed as cell membrane damage at 5 x MIC incubated for 2 hrs by DAPI staining based assay | Staphylococcus aureus | 1 | subcellular format | Scientific Literature | ||
| 11. | ALA5255985 | B | Induction of cell membrane permeability in Staphylococcus aureus ATCC 29213 at 5 x MIC incubated for 2 hrs by TO-PRO-3 reagent flow cytometry assay | Staphylococcus aureus | 2 | subcellular format | Scientific Literature | ||
| 12. | ALA5255986 | B | Induction of cell membrane permeability in methicillin-resistant Staphylococcus aureus 2 at 5 x MIC incubated for 2 hrs by TO-PRO-3 reagent flow cytometry assay | Staphylococcus aureus | 2 | subcellular format | Scientific Literature | ||
| 13. | ALA5255988 | B | Induction of membrane depolarization in Staphylococcus aureus ATCC 29213 at 5 x MIC incubated for 2 hrs by DiOC23 dye based based flow cytometry | Staphylococcus aureus | 2 | subcellular format | Scientific Literature | ||
| 14. | ALA5255989 | B | Induction of membrane depolarization in methicillin-resistant Staphylococcus aureus 2 at 5 x MIC incubated for 2 hrs by DiOC23 dye based based flow cytometry | Staphylococcus aureus | 2 | subcellular format | Scientific Literature | ||
| 15. | ALA5255990 | B | Induction of cell membrane disruption in Staphylococcus aureus ATCC 29213 assessed as increase in protein leakage at 5 x MIC incubated for 2 hrs by coomassie brilliant blue dye assay | Staphylococcus aureus | 2 | subcellular format | Scientific Literature | ||
| 16. | ALA5255991 | B | Induction of cell membrane disruption in methicillin-resistant Staphylococcus aureus 2 assessed as increase in protein leakage at 5 x MIC incubated for 2 hrs by coomassie brilliant blue dye assay | Staphylococcus aureus | 2 | subcellular format | Scientific Literature | ||
| 17. | ALA5255992 | B | Induction of cell membrane disruption in Staphylococcus aureus ATCC 29213 assessed as increase in intracellular vanomycin content at 10 x MIC incubated for 2 hrs by UPLC analysis | Staphylococcus aureus | 1 | subcellular format | Scientific Literature | ||
| 18. | ALA5255338 | B | Induction of membrane depolarization in methicillin-resistant Staphylococcus aureus USA300 assessed as disruption of transmembrane electrical potential by DiSC3(5) dye-based fluorescence assay | Staphylococcus aureus | 3 | subcellular format | Scientific Literature | ||
| 19. | ALA5255339 | B | Induction of membrane depolarization in methicillin-resistant Staphylococcus aureus USA300 assessed as disruption of transmembrane proton gradient by DiSC3(5) dye-based fluorescence assay | Staphylococcus aureus | 1 | subcellular format | Scientific Literature | ||
| 20. | ALA5255343 | B | Induction of membrane depolarization in methicillin-resistant Staphylococcus aureus USA300 assessed as measuring minimum effective concentration by DiSC3(5) dye-based fluorescence assay | Staphylococcus aureus | 16 | subcellular format | Scientific Literature |
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