| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4123767 | B | Binding affinity to Escherichia coli supercoiled pBR322 DNA assessed as DNA structural variation at 0.1 to 0.5 molar ratio per nucleotide incubated for 24 hrs under dark condition by ethidium bromide staining based agarose gel electrophoresis | Escherichia coli | 1 | ALA4118201 | nucleic acid format | Scientific Literature | |
| 2. | ALA4123768 | B | Binding affinity to Escherichia coli supercoiled pBR322 DNA assessed as 0 to 2 cross links per DNA molecule at 0.005 molar ratio per nucleotide incubated for 24 hrs under dark condition by tapping mode atomic force microscopic analysis (Rvb = 49%) | Escherichia coli | 1 | ALA4118201 | nucleic acid format | Scientific Literature | |
| 3. | ALA4123769 | B | Binding affinity to Escherichia coli supercoiled pBR322 DNA assessed as 3 to 5 cross links per DNA molecule at 0.005 molar ratio per nucleotide incubated for 24 hrs under dark condition by tapping mode atomic force microscopic analysis (Rvb = 37%) | Escherichia coli | 1 | ALA4118201 | nucleic acid format | Scientific Literature | |
| 4. | ALA4123770 | B | Binding affinity to Escherichia coli supercoiled pBR322 DNA assessed as 6 to 8 cross links per DNA molecule at 0.005 molar ratio per nucleotide incubated for 24 hrs under dark condition by tapping mode atomic force microscopic analysis (Rvb = 12%) | Escherichia coli | 1 | ALA4118201 | nucleic acid format | Scientific Literature | |
| 5. | ALA4123771 | B | Binding affinity to Escherichia coli supercoiled pBR322 DNA assessed as 9 to 10 cross links per DNA molecule at 0.005 molar ratio per nucleotide incubated for 24 hrs under dark condition by tapping mode atomic force microscopic analysis (Rvb = 2%) | Escherichia coli | 1 | ALA4118201 | nucleic acid format | Scientific Literature | |
| 6. | ALA4123772 | B | Binding affinity to Escherichia coli supercoiled pBR322 DNA assessed as more than 10 cross links per DNA molecule at 0.005 molar ratio per nucleotide incubated for 24 hrs under dark condition by tapping mode atomic force microscopic analysis (Rvb = 1%) | Escherichia coli | 1 | ALA4118201 | nucleic acid format | Scientific Literature | |
| 7. | ALA4123773 | B | Binding affinity to Escherichia coli supercoiled pBR322 DNA assessed as supercoiled areas of plasmid DNA at 0.005 molar ratio per nucleotide incubated for 24 hrs under dark condition by tapping mode atomic force microscopic analysis (Rvb = 3.5%) | Escherichia coli | 1 | ALA4118201 | nucleic acid format | Scientific Literature | |
| 8. | ALA4123774 | B | Binding affinity to Escherichia coli supercoiled pBR322 DNA assessed as DNA undergoing cross links at 0.005 molar ratio per nucleotide incubated for 24 hrs under dark condition by tapping mode atomic force microscopic analysis | Escherichia coli | 1 | ALA4118201 | nucleic acid format | Scientific Literature | |
| 9. | ALA4123775 | B | Binding affinity to Escherichia coli supercoiled pBR322 DNA assessed as DNA undergoing kinks at 0.005 molar ratio per nucleotide incubated for 24 hrs under dark condition by tapping mode atomic force microscopic analysis | Escherichia coli | 1 | ALA4118201 | nucleic acid format | Scientific Literature | |
| 10. | ALA4135396 | B | Inhibition of H2O2-induced Escherichia coli DH5alpha genomic DNA damage at 25 to 250 uL after 24 hrs by ethidium-bromide staining-based agarose gel electrophoresis | Escherichia coli DH5[alpha] | 6 | ALA4130507 | nucleic acid format | Scientific Literature | |
| 11. | ALA4141855 | A | Induction of Escherichia coli pBR322 DNA cleavage at 20 uM incubated in dark condition by agarose gel electrophoresis | Escherichia coli | 3 | ALA4138165 | nucleic acid format | Scientific Literature | |
| 12. | ALA4141856 | B | Induction of Escherichia coli pBR322 DNA cleavage at 20 uM incubated in presence of UV-light for 1 hr by agarose gel electrophoresis | Escherichia coli | 3 | ALA4138165 | nucleic acid format | Scientific Literature | |
| 13. | ALA4142333 | B | Binding affinity to Escherichia coli pUC18 DNA assessed as protection against DNase1-mediated cleavage at 250 to 700 uM preincubated for 30 mins followed by DNase1 addition measured after 5 mins by 1% agarose gel based UV-transilluminator analysis | Escherichia coli | 1 | ALA4138186 | nucleic acid format | Scientific Literature | |
| 14. | ALA4142334 | B | Binding affinity to Escherichia coli pUC18 DNA assessed as protection against DNase1-mediated cleavage at 500 uM preincubated for 30 mins followed by DNase1 addition measured after 5 mins by 1% agarose gel based UV-transilluminator analysis | Escherichia coli | 1 | ALA4138186 | nucleic acid format | Scientific Literature | |
| 15. | ALA4144229 | B | Induction of methicillin-resistant Staphylococcus aureus DNA intercalation assessed as compound-DNA complex formation incubated for 1 hr by UV-visible absorption spectroscopy | Staphylococcus aureus | 1 | ALA4138260 | nucleic acid format | Scientific Literature | |
| 16. | ALA4146995 | B | Induction of Escherichia coli pBR322 DNA intercalation assessed as transformation of topoisomerase1-relaxed pBR322 DNA in to supercoiled DNA preincubated for 10 mins followed by topoisomerase-1 addition measured after 30 mins by agarose gel electrophoresis method | Escherichia coli | 1 | ALA4145480 | nucleic acid format | Scientific Literature | |
| 17. | ALA4146996 | B | Induction of Escherichia coli pBR322 DNA intercalation assessed as transformation of topoisomerase1-relaxed pBR322 DNA in to supercoiled DNA up to 100 uM preincubated for 10 mins followed by topoisomerase-1 addition measured after 30 mins by agarose gel electrophoresis method | Escherichia coli | 2 | ALA4145480 | nucleic acid format | Scientific Literature | |
| 18. | ALA4146997 | B | Inhibition of ethidium bromide binding to Escherichia coli pBR322 DNA up to 100 uM by fluorescence assay | Escherichia coli | 2 | ALA4145480 | nucleic acid format | Scientific Literature | |
| 19. | ALA4147334 | B | Binding affinity to drug-resistant Acinetobacter baumanii DNA by UV-vis spectroscopic analysis | Acinetobacter baumannii | 1 | ALA4145497 | nucleic acid format | Scientific Literature | |
| 20. | ALA4147335 | B | Binding affinity to drug-resistant Acinetobacter baumanii DNA assessed as hyperchromic effect up to 2.5 10'-5mol/L by UV-vis spectroscopic analysis | Acinetobacter baumannii | 1 | ALA4145497 | nucleic acid format | Scientific Literature |
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