# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA615427 | Binding | Inhibition of human 3-phosphoinositide-dependent protein kinase 1 at 10 uM | Homo sapiens | 2 | ALA1145082 | single protein format | Scientific Literature | |
2. | ALA1292114 | Binding | Inhibition of PDK1 | 1 | ALA1287711 | single protein format | Scientific Literature | ||
3. | ALA1054895 | Binding | Binding affinity to PDK1 (50 to 359) by isothermal titration calorimetry | 34 | ALA1153471 | single protein format | Scientific Literature | ||
4. | ALA1054896 | Binding | Binding affinity to GST-PDK1 L155S mutant expressed in HEK293 cells at 2 uM | Homo sapiens | 1 | ALA1153471 | cell-based format | Scientific Literature | |
5. | ALA1054897 | Binding | Binding affinity to GST-PDK1 L155S mutant expressed in HEK293 cells at 20 uM | Homo sapiens | 1 | ALA1153471 | cell-based format | Scientific Literature | |
6. | ALA1054898 | Binding | Binding affinity to GST-PDK1 V127T mutant expressed in HEK293 cells at 2 uM | Homo sapiens | 1 | ALA1153471 | cell-based format | Scientific Literature | |
7. | ALA1054899 | Binding | Binding affinity to wild type recombinant GST-PDK1 expressed in HEK293 cells assessed as maximum enzyme activation | 34 | ALA1153471 | cell-based format | Scientific Literature | ||
8. | ALA1054900 | Binding | Binding affinity to wild type recombinant GST-PDK1 expressed in HEK293 cells assessed as 50% enzyme activation relative to basal activity | 34 | ALA1153471 | cell-based format | Scientific Literature | ||
9. | ALA1054901 | Binding | Binding affinity to wild type recombinant GST-PDK1 expressed in HEK293 cells at 2 uM | 1 | ALA1153471 | cell-based format | Scientific Literature | ||
10. | ALA1054902 | Binding | Binding affinity to wild type recombinant GST-PDK1 expressed in HEK293 cells at 20 uM | 1 | ALA1153471 | cell-based format | Scientific Literature | ||
11. | ALA1054903 | Binding | Binding affinity to GST-PDK1 V127T mutant expressed in HEK293 cells at 20 uM | Homo sapiens | 1 | ALA1153471 | cell-based format | Scientific Literature | |
12. | ALA1054904 | Binding | Binding affinity to GST-PDK1 I119A mutant expressed in HEK293 cells at 2 uM | Homo sapiens | 2 | ALA1153471 | cell-based format | Scientific Literature | |
13. | ALA1054905 | Binding | Binding affinity to GST-PDK1 I119A mutant expressed in HEK293 cells at 20 uM | Homo sapiens | 2 | ALA1153471 | cell-based format | Scientific Literature | |
14. | ALA1061083 | Binding | Percentage PDK1 activity remaining in the presence of 10uM inhibitor | Homo sapiens | 24 | ALA1150976 | single protein format | Scientific Literature | |
15. | ALA1061084 | Binding | Percentage PDK1 activity remaining in the presence of 2uM inhibitor | Homo sapiens | 1 | ALA1150976 | single protein format | Scientific Literature | |
16. | ALA1061922 | Binding | Binding constant for full-length PDPK1 | Homo sapiens | 38 | ALA1150977 | single protein format | Scientific Literature | |
17. | ALA1063720 | Binding | Percentage PDK1 activity remaining in the presence of 0.01uM inhibitor | Homo sapiens | 3 | ALA1150976 | single protein format | Scientific Literature | |
18. | ALA1052131 | Binding | Percent residual PDK1 activity in the presence of 10uM inhibitor | 3 | ALA1150975 | single protein format | Scientific Literature | ||
19. | ALA1062851 | Binding | Percentage PDK1 activity remaining in the presence of 0.1uM inhibitor | Homo sapiens | 7 | ALA1150976 | single protein format | Scientific Literature | |
20. | ALA1063811 | Binding | Percentage PDK1 activity remaining in the presence of 1uM inhibitor | Homo sapiens | 33 | ALA1150976 | single protein format | Scientific Literature |