# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA873411 | B | Binding affinity towards mouse Prostanoid EP1 receptor in CHO cells. | 17 | cell-based format | Scientific Literature | |||
2. | ALA766142 | B | Evaluated for its competitive binding affinity towards mouse Prostanoid EP1 receptor in CHO cells expressing prostanoid receptor | 20 | cell-based format | Scientific Literature | |||
3. | ALA763180 | B | Affinity for mouse Prostanoid EP1 receptor expressed in CHO cells | Mus musculus | 13 | cell-based format | Scientific Literature | ||
4. | ALA828212 | B | Binding affinity for mouse Prostanoid EP1 receptor | Mus musculus | 13 | single protein format | Scientific Literature | ||
5. | ALA830428 | B | Ability to inhibit the binding of [3H]PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP1 | Mus musculus | 14 | cell-based format | Scientific Literature | ||
6. | ALA2038097 | B | Displacement of [3H]PGE2 from mouse EP1 receptor expressed in CHO cells after 20 mins by scintillation counting | Mus musculus | 29 | cell-based format | Scientific Literature | ||
7. | ALA1815358 | B | Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 20 mins by liquid scintillation counting | Mus musculus | 11 | cell-based format | Scientific Literature | ||
8. | ALA1821222 | B | Displacement of [3H]PGE2 from mouse prostaglandin EP1 receptor expressed in CHO cells after 60 mins by liquid scintillation counting | Mus musculus | 11 | cell-based format | Scientific Literature | ||
9. | ALA1932308 | B | Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 20 mins by liquid scintillation counter | Mus musculus | 27 | cell-based format | Scientific Literature | ||
10. | ALA1936147 | B | Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 20 mins by liquid scintillation counting | Mus musculus | 16 | cell-based format | Scientific Literature | ||
11. | ALA1961330 | B | Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 60 mins by scintillation counting | Mus musculus | 22 | cell-based format | Scientific Literature | ||
12. | ALA1073243 | B | Displacement of [3H]PGE2 from mouse EP1 receptor expressed in CHO cells by liquid scintillation counting | Mus musculus | 19 | cell-based format | Scientific Literature | ||
13. | ALA1070315 | B | Displacement of [3H]PGE2 from mouse EP1 receptor expressed in CHO cell membrane | Mus musculus | 6 | cell-based format | Scientific Literature | ||
14. | ALA1074318 | B | Displacement of [3H]PGE2 from mouse EP1 receptor expressed in CHO cells by liquid scintillation counting | Mus musculus | 7 | cell-based format | Scientific Literature | ||
15. | ALA1104421 | B | Displacement of [3H]PGE2 from mouse EP1 receptor expressed in CHO cells after 60 mins by scintillation counter | Mus musculus | 10 | cell-based format | Scientific Literature | ||
16. | ALA1117300 | B | Displacement of [3H]PGE2 from mouse EP1 receptor expressed in CHO cells after 20 mins by liquid scintillation counting | Mus musculus | 23 | cell-based format | Scientific Literature | ||
17. | ALA2320396 | F | Antagonist activity at mouse EP1 receptor expressed in CHOK1 cells assessed as inhibition of 17PTPGE2-induced calcium influx at >100 uM | Mus musculus | 1 | cell-based format | Scientific Literature | ||
18. | ALA2320404 | F | Antagonist activity at mouse EP1 receptor expressed in CHOK1 cells assessed as inhibition of 17PTPGE2-induced calcium influx | Mus musculus | 14 | cell-based format | Scientific Literature | ||
19. | ALA3887505 | B | Inhibition Assay: The cells expressing mouse EP1 receptor were seeded at 104 cells/well in 96-well plates and cultured for 2 days with 10% Fetal Bovine Serum (FBS)/alpha Modified Eagle Medium (alphaMEM) in the incubator (37° C., 5% CO2). The cells were washed with phosphate buffer, and load buffer (10% FBS/αMEM containing Fura2/AM (5 uM), indomethacin (20 uM) and probenecid (2.5 mM)) was then added to each well and cells were left standing for 1 hour. Load buffer of each well was discarded and assay buffer (Hank's Balanced Salt Solution (HBSS) containing indomethacin (2.5 mM), probenecid (2.5 mM), HEPES-NaOH (10 mM) and 0.1% (w/v) Bovine Serum Albumin (BSA)) was added to each well and plates were left at room temperature in a dark room for 1 hour. Afterwards, compounds of the present invention (10 uL) or PGE2 (10 uL) prepared with assay buffer was added to each well and intracellular calcium concentrations were measured using a Fluorescence Drug Screening System. | Mus musculus | 12 | cell-based format | BindingDB Database |