| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4400157 | B | Binding affinity to recombinant human C5a assessed as conformational change at 1 to 100 uM incubated for 1 hr at 4degC by circular dichroism analysis | Homo sapiens | 4 | ALA4396950 | single protein format | Scientific Literature | |
| 2. | ALA4400158 | B | Binding affinity to recombinant human C5a assessed as conformational change =< 1 uM at 4 degC incubated for 1 hr by circular dichroism analysis | Homo sapiens | 4 | ALA4396950 | single protein format | Scientific Literature | |
| 3. | ALA4400159 | B | Binding affinity to recombinant human C5a assessed as loss of super secondary structure at > 10 uM incubated for 1 hr at 4 degC by circular dichroism analysis | Homo sapiens | 4 | ALA4396950 | single protein format | Scientific Literature | |
| 4. | ALA4400160 | B | Induction of recombinant human C5a destabilization assessed as intrinsically disordered structure at 2 to 4 M by circular dichroism analysis | Homo sapiens | 1 | ALA4396950 | single protein format | Scientific Literature | |
| 5. | ALA4400161 | B | Induction of recombinant human C5a destabilization assessed as intrinsically disordered structure at 2 to 8 M by circular dichroism analysis | Homo sapiens | 1 | ALA4396950 | single protein format | Scientific Literature | |
| 6. | ALA4400162 | B | Induction of recombinant human C5a destabilization assessed as protein unfolding at 6 M by circular dichroism analysis | Homo sapiens | 1 | ALA4396950 | single protein format | Scientific Literature | |
| 7. | ALA4400163 | B | Binding affinity to human C5a assessed as dissociation constant after 1 hr by circular dichroism analysis | Homo sapiens | 4 | ALA4396950 | single protein format | Scientific Literature | |
| 8. | ALA4400164 | B | Binding affinity to human C5a assessed as induction of conformational change by measuring red shift in absorption maxima at 1 uM by fluorescence analysis | Homo sapiens | 2 | ALA4396950 | single protein format | Scientific Literature | |
| 9. | ALA4400165 | B | Binding affinity to human C5a assessed as loss of secondary structure by measuring red shift in absorption maxima at 10 to 100 uM by fluorescence analysis | Homo sapiens | 4 | ALA4396950 | single protein format | Scientific Literature | |
| 10. | ALA4400166 | B | Binding affinity to human C5a assessed as Potassium iodide-induced quenching by measuring Stern-Volmer quenching constant at 1 uM by fluorescence analysis (Rvb = 4.1/M) | Homo sapiens | 5 | ALA4396950 | single protein format | Scientific Literature | |
| 11. | ALA4400167 | B | Binding affinity to human C5a assessed as change in enthalpy at 80 uM by isothermal titration calorimetry | Homo sapiens | 1 | ALA4396950 | single protein format | Scientific Literature | |
| 12. | ALA4400168 | B | Induction of human recombinant C5a unfolding by circular dichroism analysis | Homo sapiens | 4 | ALA4396950 | single protein format | Scientific Literature | |
| 13. | ALA4400169 | B | Induction of human recombinant C5a destabilization assessed as protein structure helicity up to 10 uM by circular dichroism analysis (Rvb = 71%) | Homo sapiens | 4 | ALA4396950 | single protein format | Scientific Literature | |
| 14. | ALA4400170 | B | Binding affinity to human C5a assessed as induction of conformational change with no shift in absorption maxima at 1 uM by fluorescence analysis | Homo sapiens | 2 | ALA4396950 | single protein format | Scientific Literature | |
| 15. | ALA4400171 | B | Induction of recombinant human C5a destabilization assessed as intrinsically disordered structure at 8 M incubated for 1 hr by fluorescence analysis | Homo sapiens | 1 | ALA4396950 | single protein format | Scientific Literature | |
| 16. | ALA4400172 | B | Induction of recombinant human C5a destabilization assessed as protein unfolding at 6 M after 1 hr by fluorescence analysis | Homo sapiens | 1 | ALA4396950 | single protein format | Scientific Literature | |
| 17. | ALA4400173 | B | Induction of recombinant human C5a destabilization assessed as intrinsically disordered structure at 8 M incubated for overnight by fluorescence analysis | Homo sapiens | 1 | ALA4396950 | single protein format | Scientific Literature | |
| 18. | ALA4400174 | B | Induction of recombinant human C5a destabilization assessed as protein unfolding at 6 M incubated for overnight by fluorescence analysis | Homo sapiens | 1 | ALA4396950 | single protein format | Scientific Literature | |
| 19. | ALA4668571 | B | Inhibition of C5 complement protein in 2% human serum incubated for 15 mins | Homo sapiens | 4 | ALA4665679 | cell-free format | Scientific Literature |
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