| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2384216 | B | Inhibition of integrin alphaLbeta2 (unknown origin) binding to VCAM-1 in human 8866 cells after 30 mins by fibronectin mediated cell adhesion assay | Homo sapiens | 1 | ALA2380222 | cell-based format | Scientific Literature | |
| 2. | ALA3293389 | B | Antagonist activity at alphaLbeta2 integrin in human Jurkat E6.1 cells assessed as inhibition of ICAM1-mediated cell adhesion after 30 mins by fluorescence assay | Homo sapiens | 2 | ALA3286198 | cell-based format | Scientific Literature | |
| 3. | ALA3881536 | B | Inhibition of integrin alphaL beta2 receptor (unknown origin) | Homo sapiens | 9 | ALA3881521 | protein complex format | Patent Bioactivity Data | |
| 4. | ALA4604547 | B | Inhibition of human integrin alphaL beta2 assessed as reduction in integrin alphaL beta2/ICAM1 protein-protein interaction by ELISA | Homo sapiens | 3 | ALA4602673 | protein complex format | Scientific Literature | |
| 5. | ALA4604548 | B | Binding affinity to human lymphocyte integrin alphaL beta2 (Cys125 to Gly311residues) expressed in Escherichia coli XL-1B cells by isothermal titration calorimetry | Homo sapiens | 1 | ALA4602673 | cell-based format | Scientific Literature | |
| 6. | ALA4681216 | B | Agonist activity at alphaLbeta2 in human Jurkat E6.1 cells assessed as increase in cell adhesion to ICAM1 pre-incubated for 30 mins before ICAM1 and further incubated for 30 mins by nitrophenyl-N-acetyl-beta-D-glucosaminide substrate based chromogenic assay | Homo sapiens | 15 | ALA4680084 | cell-based format | Scientific Literature | |
| 7. | ALA4681217 | B | Antagonist activity at alphaLbeta2 in human Jurkat E6.1 cells assessed as reduction in cell adhesion to ICAM1 pre-incubated for 30 mins before ICAM1 and further incubated for 30 mins by nitrophenyl-N-acetyl-beta-D-glucosaminide substrate based chromogenic assay | Homo sapiens | 19 | ALA4680084 | cell-based format | Scientific Literature | |
| 8. | ALA4681239 | B | Antagonist activity at alphaLbeta2 in human Jurkat E6.1 cells assessed as reduction in ICAM-1-induced ERK1/2 phosphorylation by Western blot analysis | Homo sapiens | 1 | ALA4680084 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!