| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2363535 | F | SANGER: Inhibition of human NCI-H526 cell growth in a cell viability assay. | Homo sapiens | 129 | ALA1201861 | cell-based format | Sanger Institute Genomics of Drug Sensitivity in Cancer | |
| 2. | ALA2434157 | F | Antitumor activity against human NCI-H526 cells xenografted in mouse | Homo sapiens | 1 | ALA2429742 | cell-based format | Scientific Literature | |
| 3. | ALA3296868 | F | Antiproliferative activity against human NCI-H526 cells after 72 hrs by MTT assay | Homo sapiens | 2 | ALA3286339 | cell-based format | Scientific Literature | |
| 4. | ALA3998532 | F | Cytotoxicity against human NCI-H526 cells assessed as decrease in cell proliferation after 72 hrs by Alamar blue assay | Homo sapiens | 9 | ALA3997781 | cell-based format | Scientific Literature | |
| 5. | ALA3998561 | F | Antitumor activity against human NCI-H526 cells xenografted in athymic nude mouse assessed as tumor growth inhibition at 30 mg/kg, iv qd administered for 5 days | Homo sapiens | 1 | ALA3997781 | organism-based format | Scientific Literature | |
| 6. | ALA3998562 | F | Antitumor activity against human NCI-H526 cells xenografted in athymic nude mouse assessed as inhibition of tumor volume at 30 mg/kg, iv qd administered for 5 days measured on day 32 relative to vehicle-treated control | Homo sapiens | 1 | ALA3997781 | organism-based format | Scientific Literature | |
| 7. | ALA3998563 | F | Antitumor activity against human NCI-H526 cells xenografted in athymic nude mouse assessed as inhibition of tumor volume at 10 mg/kg, iv qd administered 3 times for every 2 days measured on day 32 relative to vehicle-treated control | Homo sapiens | 1 | ALA3997781 | organism-based format | Scientific Literature | |
| 8. | ALA3998564 | F | Antitumor activity against human NCI-H526 cells xenografted in athymic nude mouse at 30 mg/kg, iv qd administered 5 times for every 2 days | Homo sapiens | 2 | ALA3997781 | organism-based format | Scientific Literature | |
| 9. | ALA4379101 | F | Antiproliferative activity against human NCI-H526 cells assessed as reduction in cell viability | Homo sapiens | 1 | ALA4376834 | cell-based format | Scientific Literature | |
| 10. | ALA4401557 | F | Cytotoxicity against human NCI-H526 cells assessed as reduction in cell viability after 72 hrs by presto-blue assay | Homo sapiens | 7 | ALA4400541 | cell-based format | Scientific Literature | |
| 11. | ALA4401571 | F | Antitumor activity against human NCI-H526 cells xenografted in iv dosed nu/nu mouse assessed as tumor growth inhibition administered in liposomal formulation for every other day for 6 days | Homo sapiens | 1 | ALA4400541 | organism-based format | Scientific Literature | |
| 12. | ALA4401572 | F | Antitumor activity against human NCI-H526 cells xenografted in nu/nu mouse assessed as tumor growth inhibition at 10 mg/kg, iv administered in liposomal formulation for every other day for 6 days and measured on day 30 post dose relative to control | Homo sapiens | 1 | ALA4400541 | organism-based format | Scientific Literature | |
| 13. | ALA4401574 | F | Antitumor activity against human NCI-H526 cells xenografted in nu/nu mouse assessed as tumor growth inhibition at 10 mg/kg, iv administered QD for 9 days in liposomal formulation and measured on day 33 post dose relative to control | Homo sapiens | 1 | ALA4400541 | organism-based format | Scientific Literature | |
| 14. | ALA4401575 | F | Antitumor activity against human NCI-H526 cells xenografted in nu/nu mouse assessed as tumor growth inhibition at 100 mg/kg, po administered QD for 9 days in liposomal formulation and measured on day 33 post dose | Homo sapiens | 1 | ALA4400541 | organism-based format | Scientific Literature | |
| 15. | ALA4401577 | F | Antiangiogenic activity in tumors of human NCI-H526 cells xenografted in nu/nu mouse assessed as blood vessel formation by measuring CD31 intensity at 10 mg/kg, iv administered QD for 9 days in liposomal formulation and measured on day 9 post dose by IHC-staining based microscopy relative to control | Homo sapiens | 1 | ALA4400541 | organism-based format | Scientific Literature | |
| 16. | ALA4401578 | F | Induction of DNA damage in tumors of human NCI-H526 cells xenografted in nu/nu mouse assessed as increase in gammaH2AX intensity at 10 mg/kg, iv administered QD for 9 days in liposomal formulation and measured on day 6 post dose by IHC-staining based microscopy | Homo sapiens | 1 | ALA4400541 | organism-based format | Scientific Literature | |
| 17. | ALA4401579 | F | Induction of DNA damage in tumors of human NCI-H526 cells xenografted in nu/nu mouse assessed as increase in gammaH2AX intensity at 100 mg/kg, po administered QD for 9 days in liposomal formulation and measured on day 6 post dose by IHC-staining based microscopy | Homo sapiens | 1 | ALA4400541 | organism-based format | Scientific Literature | |
| 18. | ALA4401580 | F | Induction of DNA damage in tumors of human NCI-H526 cells xenografted in nu/nu mouse assessed as increase in gammaH2AX intensity at 10 mg/kg, iv administered QD for 9 days in liposomal formulation by IHC-staining based microscopy | Homo sapiens | 1 | ALA4400541 | organism-based format | Scientific Literature | |
| 19. | ALA4401583 | F | Antiangiogenic activity in tumors of human NCI-H526 cells xenografted in nu/nu mouse assessed as blood vessel formation by measuring CD31 intensity at 100 mg/kg, po administered QD for 9 days in liposomal formulation and measured on day 9 post dose by IHC-staining based microscopy relative to control | Homo sapiens | 1 | ALA4400541 | organism-based format | Scientific Literature | |
| 20. | ALA4605956 | F | Cytotoxicity against human NCI-H526 cells expressing p53 mutant assessed as reduction in cell viability measured after 5 days by CellTiter-Glo assay | Homo sapiens | 7 | ALA4602719 | cell-based format | Scientific Literature |
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