# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA943739 | F | Cytotoxicity against human DG75 cells | Homo sapiens | 3 | ALA1141321 | cell-based format | Scientific Literature | |
2. | ALA1008879 | F | Cytotoxicity against human DG75 cells after 48 hrs by MTT assay | Homo sapiens | 2 | ALA1152241 | cell-based format | Scientific Literature | |
3. | ALA1008883 | F | Antioxidant activity against ferrous ion-induced oxidative stress in human DG75 cells assessed as decrease in malondialdehyde formation at 10 ug/mL pretreated for 4 hrs before Fe2+ challenge by TBARS assay | Homo sapiens | 1 | ALA1152241 | cell-based format | Scientific Literature | |
4. | ALA1008884 | F | Antioxidant activity against ferrous ion-induced oxidative stress in human DG75 cells assessed as decrease in malondialdehyde formation at 20 ug/mL pretreated for 4 hrs before Fe2+ challenge by TBARS assay | Homo sapiens | 1 | ALA1152241 | cell-based format | Scientific Literature | |
5. | ALA1116563 | F | Antiproliferative activity against human DG75 cells after 24 to 72 hrs by alamar blue assay | Homo sapiens | 1 | ALA1154253 | cell-based format | Scientific Literature | |
6. | ALA1116568 | F | Antiproliferative activity against human DG75 cells assessed as cell viability at 50 uM after 72 hrs by alamar blue assay | Homo sapiens | 1 | ALA1154253 | cell-based format | Scientific Literature | |
7. | ALA1116570 | F | Antiproliferative activity against human DG75 cells at 50 uM after 72 hrs by alamar blue assay | Homo sapiens | 1 | ALA1154253 | cell-based format | Scientific Literature | |
8. | ALA1116573 | F | Induction of apoptosis in human DG75 cells after 72 hrs by annexin V-propidium iodide staining-based FACS analysis | Homo sapiens | 2 | ALA1154253 | cell-based format | Scientific Literature | |
9. | ALA1116576 | F | Induction of apoptosis in human DG75 cells at 10 to 50 uM after 72 hrs by annexin V-propidium iodide staining-based FACS analysis | Homo sapiens | 1 | ALA1154253 | cell-based format | Scientific Literature | |
10. | ALA1116579 | F | Induction of apoptosis in human DG75 cells at 50 uM after 72 hrs by annexin V-propidium iodide staining-based FACS analysis | Homo sapiens | 2 | ALA1154253 | cell-based format | Scientific Literature | |
11. | ALA1676757 | F | Cytotoxicity against human chemoresistant DG75 cells expressing SERT assessed as decrease in cell viability 10 or 50 uM after 72 hrs Alamar blue assay | Homo sapiens | 16 | ALA1671778 | cell-based format | Scientific Literature | |
12. | ALA1676761 | F | Induction of apoptosis in human chemoresistant DG75 cells assessed as formation of apoptotic bodies by propidium iodide FACS analysis | Homo sapiens | 1 | ALA1671778 | cell-based format | Scientific Literature | |
13. | ALA1676769 | F | Antiproliferative activity against human DG75 cells after 24 hrs Alamar blue assay | Homo sapiens | 17 | ALA1671778 | cell-based format | Scientific Literature | |
14. | ALA2344278 | F | Induction of apoptosis in human DG75 cells assessed as cell death at 2.5 uM in presence of NAC ROS inhibitor | Homo sapiens | 3 | ALA2331299 | cell-based format | Scientific Literature | |
15. | ALA2344281 | F | Induction of apoptosis in human DG75 cells assessed as increase in caspase 3/7 activation by luminescence plate reader | Homo sapiens | 3 | ALA2331299 | cell-based format | Scientific Literature | |
16. | ALA2344282 | F | Induction of apoptosis in human DG75 cells assessed as PARP cleavage by Western blotting analysis | Homo sapiens | 3 | ALA2331299 | cell-based format | Scientific Literature | |
17. | ALA2344290 | F | Induction of apoptosis in human DG75 cells assessed as cell death at 2.5 uM measured after 24 hrs by flow cytometry | Homo sapiens | 3 | ALA2331299 | cell-based format | Scientific Literature | |
18. | ALA2344293 | F | Induction of apoptosis in human DG75 cells assessed as decrease in cells at G2/M phase measured at 2.5 uM after 24 hrs by propidium iodide assay | Homo sapiens | 6 | ALA2331299 | cell-based format | Scientific Literature | |
19. | ALA2344295 | F | Induction of apoptosis in human DG75 cells assessed as increase in cells at G2/M phase measured at 2.5 uM after 24 hrs by propidium iodide assay | Homo sapiens | 1 | ALA2331299 | cell-based format | Scientific Literature | |
20. | ALA2344297 | F | Induction of apoptosis in human DG75 cells assessed as cell death at 2.5 uM after 24 hrs by flow cytometry (Rvb = 0.8 +/- 0.25%) | Homo sapiens | 4 | ALA2331299 | cell-based format | Scientific Literature |