# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2363239 | F | SANGER: Inhibition of human GCIY cell growth in a cell viability assay. | Homo sapiens | 137 | cell-based format | Sanger Institute Genomics of Drug Sensitivity in Cancer | ||
2. | ALA4688758 | F | Cytotoxicity against human GCIY cells assessed as reduction in cell viability measured after 48 hrs by MTS/CellTiter96 aqueous one solution cell proliferation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA4688760 | F | Induction of apoptosis in human GCIY cells assessed as activation of caspase 3 measured after 5 to 35 hrs by fluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
4. | ALA4688761 | F | Induction of apoptosis in human GCIY cells assessed as activation of caspase 3 at 1 to 10 uM by fluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
5. | ALA4688762 | F | Induction of apoptosis in human GCIY cells assessed as activation of caspase 9 measured after 5 to 35 hrs by fluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA4688763 | F | Induction of apoptosis in human GCIY cells assessed as activation of caspase 9 at 1 to 10 uM by fluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
7. | ALA4688768 | F | Cell cycle arrest in human GCIY cells assessed as accumulation at G0/G1 phase at 0.1 uM measured after 24 hrs by propidium iodide staining based Muse cell analyzer (Rvb = 43 +/- 2.2 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
8. | ALA4688769 | F | Cell cycle arrest in human GCIY cells assessed as accumulation at S phase at 0.1 uM measured after 24 hrs by propidium iodide staining based Muse cell analyzer (Rvb = 25.7 +/- 0.7 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
9. | ALA4688770 | F | Cell cycle arrest in human GCIY cells assessed as accumulation at G2/M phase at 0.1 uM measured after 24 hrs by propidium iodide staining based Muse cell analyzer (Rvb = 28.9 +/- 1.3 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
10. | ALA4688771 | F | Cell cycle arrest in human GCIY cells assessed as accumulation at G0/G1 phase at 0.3 uM measured after 24 hrs by propidium iodide staining based Muse cell analyzer (Rvb = 43 +/- 2.2 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
11. | ALA4688772 | F | Cell cycle arrest in human GCIY cells assessed as accumulation at S phase at 0.3 uM measured after 24 hrs by propidium iodide staining based Muse cell analyzer (Rvb = 25.7 +/- 0.7 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
12. | ALA4688773 | F | Cell cycle arrest in human GCIY cells assessed as accumulation at G2/M phase at 0.3 uM measured after 24 hrs by propidium iodide staining based Muse cell analyzer (Rvb = 28.9 +/- 1.3 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
13. | ALA4688780 | F | Antitumor activity against human GCIY cells xenografted in KSN/Slc nude mouse assessed as reduction in tumor size at 40 mg/kg, ip administered twice a week for 4 weeks starting from day 4 post inoculation by vernier caliper method | Homo sapiens | 3 | organism-based format | Scientific Literature | ||
14. | ALA5245584 | F | Antiproliferative activity against human GCIY cells assessed as cell growth inhibition by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
15. | ALA5245599 | F | Antiproliferative activity against human GCIY cells assessed as cell growth inhibition measured after 72 hrs | Homo sapiens | 10 | cell-based format | Scientific Literature |