# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2363336 | Functional | SANGER: Inhibition of human KLE cell growth in a cell viability assay. | Homo sapiens | 123 | ALA1201861 | cell-based format | Sanger Institute Genomics of Drug Sensitivity in Cancer | |
2. | ALA4624531 | Functional | Antiproliferative activity against human KLE cells assessed as inhibition of cell viability by CCK8 assay | Homo sapiens | 2 | ALA4622903 | cell-based format | Scientific Literature | |
3. | ALA4624536 | Functional | Potency index, ratio of medroxyprogesterone acetate IC50 to test compound IC50 for antiproliferative activity against human KLE cells assessed as inhibition of cell viability by CCK8 assay | Homo sapiens | 1 | ALA4622903 | cell-based format | Scientific Literature | |
4. | ALA4624541 | Functional | Inhibition of colony formation in progesterone resistant human KLE cells | Homo sapiens | 1 | ALA4622903 | cell-based format | Scientific Literature | |
5. | ALA4624544 | Functional | Antimigratory activity against progesterone-resistant human KLE cells assessed as reduction in cell migration at 10 uM after 48 hrs by transwell assay | Homo sapiens | 2 | ALA4622903 | cell-based format | Scientific Literature | |
6. | ALA4624551 | Functional | Induction of apoptosis in progesterone-resistant human KLE cells assessed as early apoptotic cells at 10 uM after 48 hrs by Annexin-V/PI staining based flow cytometry (Rvb = 2.85%) | Homo sapiens | 1 | ALA4622903 | cell-based format | Scientific Literature | |
7. | ALA4624552 | Functional | Induction of apoptosis in progesterone-resistant human KLE cells assessed as late apoptotic cells at 10 uM after 48 hrs by Annexin-V/PI staining based flow cytometry (Rvb = 3.56%) | Homo sapiens | 1 | ALA4622903 | cell-based format | Scientific Literature | |
8. | ALA4624553 | Functional | Induction of apoptosis in progesterone-resistant human KLE cells assessed as necrotic cells at 10 uM after 48 hrs by Annexin-V/PI staining based flow cytometry (Rvb = 1.30%) | Homo sapiens | 1 | ALA4622903 | cell-based format | Scientific Literature | |
9. | ALA4624554 | Functional | Induction of apoptosis in progesterone-resistant human KLE cells assessed as early apoptotic cells at 20 uM after 48 hrs by Annexin-V/PI staining based flow cytometry (Rvb = 2.85%) | Homo sapiens | 1 | ALA4622903 | cell-based format | Scientific Literature | |
10. | ALA4624555 | Functional | Induction of apoptosis in progesterone-resistant human KLE cells assessed as late apoptotic cells at 20 uM after 48 hrs by Annexin-V/PI staining based flow cytometry (Rvb = 3.56%) | Homo sapiens | 1 | ALA4622903 | cell-based format | Scientific Literature | |
11. | ALA4624556 | Functional | Induction of apoptosis in progesterone-resistant human KLE cells assessed as necrotic cells at 20 uM after 48 hrs by Annexin-V/PI staining based flow cytometry (Rvb = 1.30%) | Homo sapiens | 1 | ALA4622903 | cell-based format | Scientific Literature | |
12. | ALA4624558 | Functional | Induction of apoptosis in progesterone-resistant human KLE cells after 48 hrs by Annexin-V/PI staining based flow cytometry | Homo sapiens | 1 | ALA4622903 | cell-based format | Scientific Literature | |
13. | ALA4817549 | Functional | Antiproliferative activity against human KLE cells expressing wild type KRAS assessed as reduction in cell growth upto 30 uM incubated for 72 hrs by CyQuant proliferation assay | Homo sapiens | 3 | ALA4814013 | cell-based format | Scientific Literature | |
14. | ALA5262334 | Functional | Cytotoxicity against human KLE cells measured after 8 days | Homo sapiens | 2 | ALA5260810 | cell-based format | Scientific Literature |