# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3609985 | Functional | Positive allosteric modulation of rat muscarinic M1 receptor expressed in CHO cells assessed as basal and acetylcholine-stimulated Ca2+ level by FLIPR assay | Rattus norvegicus | 10 | ALA3608283 | cell-based format | Scientific Literature | |
2. | ALA3824950 | Functional | Positive allosteric modulation at rat muscarinic acetylcholine receptor M1 expressed in CHO cells assessed as potentiation of acetylcholine-induced calcium mobilization | Rattus norvegicus | 11 | ALA3822368 | cell-based format | Scientific Literature | |
3. | ALA3824951 | Functional | Positive allosteric modulation at rat muscarinic acetylcholine receptor M1 expressed in CHO cells assessed as potentiation of acetylcholine-induced calcium mobilization in relative to acetylcholine | Rattus norvegicus | 7 | ALA3822368 | cell-based format | Scientific Literature | |
4. | ALA621841 | Functional | Compound tested for relative response using 1 uM ACh as agonist against AChM1 receptor. | 1 | ALA1131086 | assay format | Scientific Literature | ||
5. | ALA714427 | Binding | Ability to displace [3H]pirenzepine (PZ) from M1 receptor in rat cortex homogenate | 4 | ALA1127012 | tissue-based format | Scientific Literature | ||
6. | ALA714428 | Binding | Affinity constant against Muscarinic acetylcholine receptor M1 of rat cerebral cortex. | 1 | ALA1126048 | tissue-based format | Scientific Literature | ||
7. | ALA714429 | Binding | Affinity constant to Muscarinic acetylcholine receptor M1 of rat cerebral cortex | 1 | ALA1126048 | tissue-based format | Scientific Literature | ||
8. | ALA714430 | Functional | Compound was measured for percentage of intrinsic activity against M1 muscarinic receptor, by stimulation of phosphatidylinositol (PI) hydrolysis in rat hippocampal slices | 4 | ALA1128612 | tissue-based format | Scientific Literature | ||
9. | ALA877252 | Binding | Pseudo hill coefficient at M1 receptor | 1 | ALA1124162 | single protein format | Scientific Literature | ||
10. | ALA711165 | Binding | Pseudo hill coefficient at Muscarinic acetylcholine receptor M1 | 2 | ALA1124162 | single protein format | Scientific Literature | ||
11. | ALA711166 | Binding | Binding affinity at [3H]PZ radiolabeled muscarinic M1 receptor in rat cortex. | 18 | ALA1127058 | tissue-based format | Scientific Literature | ||
12. | ALA858414 | Binding | Affinity constant measured against M1 muscarinic receptor in rat cortex | 4 | ALA1126912 | assay format | Scientific Literature | ||
13. | ALA711327 | Binding | The binding affinity was measured on muscarine M1 receptor using [3H]- pirenzepine as radioligand. | 2 | ALA1127031 | single protein format | Scientific Literature | ||
14. | ALA719078 | Binding | Compound is tested for displacement of [3H]pirenzepine at Metabotropic glutamate receptor 1 in Rat brain homogenate. | 8 | ALA1133588 | tissue-based format | Scientific Literature | ||
15. | ALA821485 | Functional | Percent increase in Arachidonic acid (AA) release using CHO cells, transfected with rat muscarinic m1 acetylcholine receptor (AChR) | 2 | ALA1126234 | cell-based format | Scientific Literature | ||
16. | ALA846207 | Binding | Tested for muscarinic binding affinity (Kapp) with 1 nM [3H]pirenzepine in rat cortex | 5 | ALA1123768 | assay format | Scientific Literature | ||
17. | ALA846208 | Binding | Tested for muscarinic binding affinity (Kapp) with 1 nM [3H]pirenzepine in rat cortex. Value in parentheses is NH- Hill coefficient of the displacement curve | 1 | ALA1123768 | assay format | Scientific Literature | ||
18. | ALA844383 | Binding | Binding affinity by the displacement of [3H]NMS binding to A9 L cells transfected with muscarinic M1 receptor of rat brain | Rattus norvegicus | 4 | ALA1126666 | cell-based format | Scientific Literature | |
19. | ALA844384 | Binding | Binding affinity by the displacement of [3H]NMS binding to muscarinic M1 receptor of rat brain | Rattus norvegicus | 7 | ALA1126666 | assay format | Scientific Literature | |
20. | ALA844386 | Binding | Binding affinity against m-AcChR subtype M1 of rat cerebral cortex. | 3 | ALA1126048 | tissue-based format | Scientific Literature |