# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA734445 | F | In vivo muscarinic effect of [3H]pirenzepine-induced hypothermia against central M2 receptor in mice at dose under 30 mg/kg sc (2 degree Celsius) | Mus musculus | 2 | ALA1126758 | organism-based format | Scientific Literature | |
2. | ALA737489 | F | Minimum dose required for subcutaneous administration to improve scopolamine-induced impairment of passive avoidance task in mouse(anti-amnesic effect) | 21 | ALA1126758 | organism-based format | Scientific Literature | ||
3. | ALA744480 | B | Compound was evaluated for the competitive inhibition of [3H]methylscopolamine binding to Muscarinic acetylcholine receptor M2 of mouse cerebral cortex | Mus musculus | 9 | ALA1125408 | tissue-based format | Scientific Literature | |
4. | ALA744481 | B | Compound was evaluated for the competitive inhibition of [3H]methylscopolamine binding to muscarinic acetylcholine receptor M2 of mouse cerebral cortex | Mus musculus | 6 | ALA1125408 | tissue-based format | Scientific Literature | |
5. | ALA744482 | B | Ability to displace [3H]methylscopolamine ([3H]NMS) from mouse cerebral cortex | Mus musculus | 5 | ALA1125532 | tissue-based format | Scientific Literature | |
6. | ALA744483 | B | Ability to displace [3H]methylscopolamine ([3H]NMS) from mouse cerebral cortex | Mus musculus | 1 | ALA1125532 | tissue-based format | Scientific Literature | |
7. | ALA744484 | B | Ability to displace [3H]oxotremorine ([3H]-OXO-M) from mouse cerebral cortex | Mus musculus | 6 | ALA1125532 | tissue-based format | Scientific Literature | |
8. | ALA880141 | B | Ability to displace [3H]oxotremorine ([3H]OXO-M) from mouse cerebral cortex | Mus musculus | 1 | ALA1125532 | tissue-based format | Scientific Literature | |
9. | ALA744485 | B | Ratio of Ki of [3H]-NMS binding to that of [3H]OXO-M binding. | Mus musculus | 6 | ALA1125532 | single protein format | Scientific Literature | |
10. | ALA744486 | B | Selectivity was defined as the ratio between M2-IC50/M1-IC50 | Mus musculus | 6 | ALA1125408 | single protein format | Scientific Literature | |
11. | ALA744487 | B | Percent inhibition (high) of [3H](R)-QNB binding to Muscarinic acetylcholine receptor M2 expressed in A9 L cell line | Mus musculus | 1 | ALA1129993 | cell-based format | Scientific Literature | |
12. | ALA746839 | B | Percent inhibition (low) of [3H](R)-QNB binding to Muscarinic acetylcholine receptor M2 expressed in A9 L cell line | Mus musculus | 5 | ALA1129993 | cell-based format | Scientific Literature | |
13. | ALA746840 | B | Percent inhibition (medium) of [3H]-(R)-QNB binding to Muscarinic acetylcholine receptor M2 expressed in A9 L cell line | Mus musculus | 5 | ALA1129993 | cell-based format | Scientific Literature | |
14. | ALA746841 | B | Binding affinity (high) of [3H](R)-QNB binding to Muscarinic acetylcholine receptor M2 expressed in A9 L cell line | 1 | ALA1129993 | cell-based format | Scientific Literature | ||
15. | ALA746842 | B | Binding affinity (low) of [3H]-(R)-QNB binding to Muscarinic acetylcholine receptor M2 expressed in A9 L cell line | Mus musculus | 5 | ALA1129993 | cell-based format | Scientific Literature | |
16. | ALA858222 | B | Binding affinity (medium) of [3H](R)-QNB binding to Muscarinic acetylcholine receptor M2 expressed in A9 L cell line | Mus musculus | 5 | ALA1129993 | cell-based format | Scientific Literature |