| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2363329 | F | SANGER: Inhibition of human KARPAS-422 cell growth in a cell viability assay. | Homo sapiens | 77 | cell-based format | Sanger Institute Genomics of Drug Sensitivity in Cancer | ||
| 2. | ALA4008168 | F | Antiproliferative activity against human KARPAS422 cells harboring monoallelic Y641N EZH2 mutation assessed as reduction in cell viability measured every 3 to 4 days up to 14 days by Beckman Coulter-based method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 3. | ALA4008203 | F | Antitumor activity against human KARPAS422 cells xenografted in Balb/C nude mouse assessed as tumor regression at 300 mg/kg, po BID for 34 days | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 4. | ALA4015796 | F | Antiproliferative activity against BCL6 independent human KARPAS422 cells after 3 days by CellTiter-Glo assay | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
| 5. | ALA4027396 | F | Antitumor activity against human KARPAS422 cells harboring EZH2 Y641N mutant xenografted in mouse assessed as decrease in tumor growth at 100 mg/kg, po bid | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 6. | ALA4027399 | F | Antiproliferative activity against human KARPAS422 cells after 72 hrs by resazurin assay | Homo sapiens | 33 | cell-based format | Scientific Literature | ||
| 7. | ALA4027406 | F | Antitumor activity against human KARPAS422 cells harboring EZH2 Y641N mutant xenografted in mouse assessed as tumor regression at 300 mg/kg, po bid measured 40 days post treatment termination on day 31 | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA4027408 | F | Antitumor activity against human KARPAS422 cells harboring EZH2 Y641N mutant xenografted in mouse assessed as decrease in tumor regression at 100 mg/kg, sc qd measured 40 days post treatment termination on day 31 | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA4042399 | F | Antiproliferative activity against human KARPAS422 cells measured after 72 hrs by alamar blue assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 10. | ALA4150758 | F | Growth inhibition of human KARPAS422 cells incubated for 48 hrs by cell-titer-blue dye based assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 11. | ALA4151152 | F | Antiproliferative activity against human KARPAS422 cells after 7 days by cell-titer glo based luminescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4193879 | F | Growth inhibition of human KARPAS422 cells by CCK8 assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 13. | ALA4327378 | F | Antiproliferative activity against human KARPAS422 cells after 4 days by cell titer-glo luminescent cell viability assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 14. | ALA4327381 | F | Induction of apoptosis in human KARPAS422 cells assessed as viable cells at 4 uM after 48 hrs by AnnexinV-FITC staining-based flow cytometric analysis (Rvb = 91.3%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4327382 | F | Induction of apoptosis in human KARPAS422 cells assessed as apoptotic cells at 4 uM after 48 hrs by AnnexinV-FITC staining-based flow cytometric analysis (Rvb = 4.08%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4327383 | F | Induction of apoptosis in human KARPAS422 cells assessed as necrotic cells at 4 uM after 48 hrs by AnnexinV-FITC staining-based flow cytometric analysis (Rvb = 3.20%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4327384 | F | Induction of apoptosis in human KARPAS422 cells assessed as viable cells at 8 uM after 48 hrs by AnnexinV-FITC staining-based flow cytometric analysis (Rvb = 91.3%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4327385 | F | Induction of apoptosis in human KARPAS422 cells assessed as apoptotic cells at 8 uM after 48 hrs by AnnexinV-FITC staining-based flow cytometric analysis (Rvb = 4.08%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4327386 | F | Induction of apoptosis in human KARPAS422 cells assessed as necrotic cells at 8 uM after 48 hrs by AnnexinV-FITC staining-based flow cytometric analysis (Rvb = 3.20%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4327387 | F | Induction of apoptosis in human KARPAS422 cells assessed as viable cells at 16 uM after 48 hrs by AnnexinV-FITC staining-based flow cytometric analysis (Rvb = 91.3%) | Homo sapiens | 1 | cell-based format | Scientific Literature |
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